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Inflammatory Breast Cancer: An Update
Inflammatory breast cancer is the most deadly subtype of breast cancer because it can spread to other organs despite of multidisciplinary approach. However, the molecular characteristic of this aggressive disease is yet to be established. This book is the one of the few textbooks that summarizes the latest information dated to inflammatory breast cancer. The uniqueness of this book is that it has summarized the latest molecular and mechanistic findings, which may lead to novel diagnostic tool or therapeutic approach to fight this deadly disease.
New Aspects of Cancer Stem Cell Biology
The cancer stem cell (CSC) paradigm represents one of the most prominent breakthroughs of the last decades in tumor biology. CSCs are that subpopulation within a tumor that can survive conventional therapies and as a consequence are able to fuel tumor recurrence. Nevertheless, the biological characteristics of CSCs and even their existence, remain the main topic among tumor biologists debates. The difficulty in achieving a better definition of CSC biology may actually be explained by the plasticity of such a cell subpopulation. Indeed, the emerging view is that CSCs represent a dynamic “state” of tumor cells that can acquire stemness-related properties under specific circumstances, rathe...
Molecular Biology of Hematopoiesis 6
This volume of Molecular Biology of Hematopoiesis is dedicated to many inter national scientists and clinicians for their contribution to the field of Hematology/ Oncology presented at the 11th International Symposium on Molecular Biology of Hematopoiesis, which was held in Bormio, Italy, June 25-29, 1998. The continuous support of the Presidents of the meeting, Professor F. Takaku, President of Jichi University, and E. D. Thomas, Nobel Laureate, was greatly acknowledged, especially Professor Takaku, for his vision and support for development of gene therapy in Japan. New information on BMT for autoimmune disease and organ transplantation was presented at the symposium and is published in th...
Topics on Cervical Cancer With an Advocacy for Prevention
Cervical Cancer is one of the leading cancers among women, especially in developing countries. Prevention and control are the most important public health strategies. Empowerment of women, education, "earlier" screening by affordable technologies like visual inspection, and treatment of precancers by cryotherapy/ LEEP are the most promising interventions to reduce the burden of cervical cancer.Dr Rajamanickam Rajkumar had the privilege of establishing a rural population based cancer registry in South India in 1996, as well as planning and implementing a large scale screening program for cervical cancer in 2000. The program was able to show a reduction in the incidence rate of cervical cancer by 25%, and reduction in mortality rate by 35%. This was the greatest inspiration for him to work on cerrvical cancer prevention, and he edited this book to inspire others to initiate such programs in developing countries. InTech - Open Access Publisher plays a major role in this crusade against cancer, and the authors have contributed to it very well.
Healthcare Funding and Christian Ethics
A necessary book for healthcare professionals and theologians struggling with moral questions about rationing in healthcare. This book outlines a Christian ethical basis for how decisions about health care funding and priority-setting ought to be made.
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ImmunOncology – La mémoire and the anātman
A biotechnology educational paper illustrating the immune system and its involvement in tumor proliferation, comprising with a new glimpse about the genesis of vaccination and the spontaneous symbiotic reassembling that shaping humankind and its microbiome.
Les cibles intracytoplasmiques
L’identification et le rôle des cibles intracytoplasmiques ont, pour certaines d’entre elles, permis des développements spectaculaires. Les applications les plus avancées concernent les antityrosines kinases et il est possible que de nouveaux inhibiteurs soient rapidement utilisés dans d’autres syndromes myéloprolifératifs. Une meilleure compréhension du protéasome a permis des résultats intéressants dans le myélome multiple, et des développements pourraient voir le jour dans d’autres hémopathies. Pour d’autres cibles apparemment prometteuses, les applications tardent à se préciser... Tel un tireur d’élite, la thérapie ciblée idéale pourrait se vanter d’une f...
Les cibles de l'immunité
La survenue de la maladie cancéreuse témoigne de l'incapacité du système immunitaire à contrôler la croissance tumorale. Cette tolérance explique les difficultés de l'immunothérapie anticancéreuse. Cependant grâce aux récents progrès de la recherche en immunologie, de nouveaux espoirs thérapeutiques sont nés. Cet ouvrage très didactique présente les dernières avancées et des pistes thérapeutiques très prometteuses en immunothérapie : L'ADCC et immunothérapie anticancéreuseCellules natural killer et immunité antitumoraleInteractions entre le système immunitaire et les traitements conventionnels des cancersInterféron et immunité anticancéreuseImmunothérapie adoptive et cancerStratégies vaccinales et cancerLes lymphocytes T régulateurs : rôle et ciblage dans le cancer
