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"Today, we are exposed to an ever-growing number of chemicals in the environment and there is an increasing awareness of the effects of these chemicals on the ovaries. As such, the potential for xenobiotic-induced infertility needs to be better understood. Additionally, menopause-associated disorders are of growing health concern in view of the fact that by the year 2025, 19.5% of the population of the U.S. will be menopause-aged women. Exploring research into chemicals that have the potential to cause early menopause by destroying pre-antral ovarian follicles, this book is an essential resource for researchers in academia, regulatory agencies, and industry"--Provided by publisher.
In recent years, there has been an alarming increase in environmental by-products that may be harmful to ovarian function. Along with this dangerous situation, the modern trend toward delaying motherhood poses immediate concerns regarding the long-term impact of environmental risks on human fertility. The uncertainty of our reproductive future intensifies the need for a single reference that investigates the chemicals with the potential to jeopardize fertility. The only known text that deals specifically with toxicity in the ovary, Ovarian Toxicology updates our current understanding of the effects of environmental chemicals on ovarian function. This new title in the Target Organ Toxicology ...
Rising fossil fuel prices and concerns about greenhouse gas emissions are fostering a nuclear power renaissance and a revitalized uranium mining industry across the American West. In The Price of Nuclear Power, environmental sociologist Stephanie Malin offers an on-the-ground portrait of several uranium communities caught between the harmful legacy of previous mining booms and the potential promise of new economic development. Using this context, she examines how shifting notions of environmental justice inspire divergent views about nuclear power’s sustainability and equally divisive forms of social activism. Drawing on extensive fieldwork conducted in rural isolated towns such as Montice...
There is great concern regarding the reproductive and health hazards of endocrine disruptors. Research indicates that men are experiencing declining fertility and an increased incidence of prostate cancer, while women are dealing with increased infertility, early menopause, and breast cancer. As new research reveals the previously unknown risks of
The application of molecular biologic methods, recognition of neurogenic inflammatory processes, and utilization of genetic knockout animals are just some of the advances in toxicology of the upper airways in recent years. Toxicology of the Nose and Upper Airways presents a culmination of knowledge gained as a result of both human and experimental
LOCATE FREQUENTLY USED INFORMATION EASILY AND QUICKLY Working in the laboratory or office, you use a diverse assortment of basic information to design, conduct, and interpret toxicology studies and to perform risk assessments. The Second Edition of the best-selling Handbook of Toxicology gives you the information you need in a single referen
This volume presents a discussion of the biological effects produced following the metabolism of xenobiotic chemicals to chemically reactive metabolites, i.e., toxic and carcinogenic effects, which have been the basis of all five earlier volumes in this series. In particular, this volume devotes sections to structure-activity relationships, recent advances in the understanding of the chemistry of reactive metabolites, and the generation and activity of reactive oxygen species with special emphasis on nitric oxide. There are also segments on DNA damage by reactive metabolites and DNA repair, tissue specific responses to BRIs, and human health effects of BRIs. The papers that comprise this volume were submitted by world class scientists who were in attendance at The Symposium on Biological Reactive Intermediates VI at the Université René Descartes, July 16-20, 2000.
Thoroughly examining the popular and expanding field of reproductive toxicology, this newly revised and expanded third edition provides the latest, cutting-edge scientific developments in this constantly evolving discipline. Reproductive Toxicology's contributors are experienced regulatory agency and Clinical Research Organization representatives w
The regulation of cell death in various reproductive tissues, as in other ma jor organ systems of the body, has become a focal point of research activity in many laboratories over the past few years. As such, the need for a "for mal" meeting to highlight recent work in this field, as well as to integrate knowledge from other sources (such as investigators working on cell death in cancer and immune function) in the broad context of identifying con served pathways that coordinate life-and-death decisions in diverse cell types, became apparent. Therefore, the goals of the Scientific Committee of the International Symposium on Cell Death in Reproductive Physiology, spon sored by Serono Symposia ...
The kidney plays a vital role in certain endocrine functions. Abnormalities caused by toxic chemicals or other interventions can have profound effects on these functions and consequently, on total functions. Toxicology of the Kidney, Third Edition is updated to reflect the latest research in this field and focuses on the correlation between anatomy