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Neurofibromatosis Type 1
Neurofibromatosis type 1 (NF1), caused by mutational inactivation of the NF1 tumour suppressor gene, is one of the most common dominantly inherited human disorders, affecting 1 in 3000 individuals worldwide. This book presents in concise fashion, but as comprehensively as possible, our current state of knowledge on the molecular genetics, molecular biology and cellular biology of this tumour predisposition syndrome. Written by internationally recognized experts in the field, the 44 chapters that constitute this edited volume provide the reader with a broad overview of the clinical features of the disease, the structure and expression of the NF1 gene, its germ line and somatic mutational spectra and genotype-phenotype relationships, the structure and function of its protein product (neurofibromin), NF1 modifying loci, the molecular pathology of NF1-associated tumours, animal models of the disease, psycho-social aspects and future prospects for therapeutic treatment.
Ophthalmic Care
Written by an international team of ophthalmic practitioners, this authoritative book is a vital resource not only for ophthalmic professionals, but for any healthcare professional who cares for patients with eye problems. In the ten years since the first edition was published, practice has moved on, as has the evidence for practice. This second edition draws on the passion and goodwill of the original team of authors, complemented by other colleagues, to fully revise and update the text in line with new findings, new practice and new and exciting treatments. The book is broadly divided into three sections. The first section considers the structure and function of the eye, as well as the bas...
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Nanoarchitectonics for Brain Drug Delivery
This book discusses basics of brain diseases and the role of nanobiotechnology in existing treatment options for neurodegenerative disorders. It begins with an overview of brain diseases and the need for novel drug-delivery approaches. It highlights the current route for the intranasal advanced drug-delivery systems for brain diseases. It also discusses innovative categories of drug-delivery systems, including mesoporous silica nanoparticles, polymeric nanocarriers, and lipid-based nanocarriers through multi-responsive DDSs and their implications in brain disorders. Features: Includes an overview of brain diseases and highlights the need for novel drug-delivery approaches Focuses on theoreti...
Handbook of Oncology Social Work
The development of this inaugural Handbook of Oncology Social Work: Psychosocial Care for People With Cancer provides a repository of the scope of oncology social workers' clinical practice, education, research, policy and program leadership in the psychosocial care of people with cancer and their families. It focuses on the unique synergy of social work perspectives, values, knowledge, and skills with the psychosocial needs of cancer patients, their families, and the health care systems in which they are treated. It addresses both the science and art of psychosocial care and identifies the increasing specialization of oncology social work related to its unique knowledge base, skills, role, ...
Women's Cancers
Patients with breast and gynaecological cancers have to contend with a large number of difficult and challenging issues. To help them to do this it is vital that their health carers are fully informed in all aspects of women's cancers. This book provides a comprehensive and meaningful picture of this oncological area, including epidemiology, histopathology, staging, genetic predisposition, sexual function, fertility, treatment and management, survivorship, and palliative care. To give this book added credibility and holistic application, contributions of women with cancer have been included, and the text is interspersed with patient accounts and experiences. Women's Cancers is essential reading for all nurses and health care professionals working in cancer care settings, as well as patients and families.
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Role Development for Doctoral Advanced Nursing Practice
2011 AJN Book of the Year Winner in Advanced Practice Nursing! "This is a unique book that will be valuable to both graduate students and professional advanced practice nurses. Since the role of the DNP graduate is evolving, this is an important contribution to the field. It focuses on the developing discussion of practice and graduate degrees in the field of nursing and provides up-to-date information about the evolving and expanding roles of DNP graduate nurses." Score: 100, 5 Stars.--Doody's Medical Reviews (2013) "This outstanding and thought provoking book...provides the knowledge to not only understand the issues and role related challenges of doctoral advanced nursing practice but the...
