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Stem Cells and Cancer Stem Cells, Volume 8
It is my hope that subsequent volumes of the series will join this volume in assisting in the more complete understanding of the causes, diagnosis, and cell-based treatment of major human diseases and debilitating tissue/organ injuries. There exists a tremendous, urgent demand by the public and the scientific community to address to cancer diagnosis, treatment, cure, and hopefully prevention. Stem Cells are nature’s indispensable gift to multicellular organisms, including humans. The contents of the volume are divided into six subheadings: Stem Cell Culture, Bone Marrow Stem Cells, Mesenchymal Stem Cells, Reprogramming and Differentiation of Stem Cells, Treatment, and Transplantation for the convenience of the readers.
Transcriptional and Translational Regulation of Stem Cells
This volume describes the latest findings on transcriptional and translational regulation of stem cells. Both transcriptional activators and repressors have been shown to be crucial for the maintenance of the stem cell state. A key element of stem cell maintenance is repression of differentiation factors or developmental genes – achieved transcriptionally, epigenetically by the Polycomb complex, and post-transcriptionally by RNA-binding proteins and microRNAs. This volume takes two approaches to this topic – (1) illustrating the general principles outlined above through a series of different stem cell examples – embryonic, iPS and adult stem cells, and (2) describing several molecular families that have been shown to have roles in regulation of multiple stem cell populations.
Glutamate Receptors in Peripheral Tissue
Glutamate receptors (GluRs) in the central nervous system have been the subject of intense investigations for several decades, providing new avenues for the understanding of excitatory neurotransmission, excitotoxicity, mechanisms of injury, and therapeutics for several acute neurological conditions, such as brain trauma, and for neurodegenerative and neuropsychiatric disorders including addictions, Alzheimer disease, etc. Evidences of GluRs beyond the central nervous system were first reported in the early 1990s. When the idea of this book was conceived, the knowledge, specificity, and functional significance of GluRs in peripheral tissues was still in its embryonic stage. From our perspect...
Hip Joint Restoration
Hip Joint Restoration is a comprehensive yet practical guide to the basic science and clinical applications of arthroscopy, arthroplasty, osteotomy and preservation surgery for the treatment of diseases and conditions of the hip. This generously illustrated text offers a comprehensive introduction to essential features of hip evaluation, the medical management of hip procedures, and treatment of specific conditions, and covers practical topics such as surgical anatomy of the hip, surgical approaches, instrumentation, and indications for arthroscopy and other surgical procedures aimed at restoration of the hip joint. Additional chapters cover clinical outcomes and equality of life following hip surgery, the current state of research and education of arthroscopic hip procedures throughout the world, other topics such as complications and rehabilitation in different patient populations. This book will be a useful resource for Orthopedic Surgeons and Osteopaths who perform open and arthroscopic hip preservation and total joint replacement, as well as for orthopedic residents and researchers.
Oxford Textbook of Rheumatology
A strong clinical emphasis is present throughout this volume from the first section of commonly presenting problems through to the section addressing problems shared with a range of other clinical sub-specialties.
The Biology and Therapeutic Application of Mesenchymal Cells, 2 Volume Set
The Biology and Therapeutic Application of Mesenchymal Cells comprehensively describes the cellular and molecular biology of mesenchymal stem cells and mesenchymal stromal cells, describing their therapeutic potential in a wide variety of preclinical models of human diseases and their mechanism of action in these preclinical models. Chapters also discuss the current status of the use of mesenchymal stem and stromal cells in clinical trials in a wide range of human diseases and disorders, for many of which there are limited, or no other, therapeutic avenues. Provides coverage on both the biology of mesenchymal stem cells and stromal cells, and their therapeutic applications Describes the ther...
New Scientist
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Enjoying Gin
Enjoying Gin gives comprehensive, practical information while offering a working guide to the pleasures, flavor intricacies, and overall enjoyment of this evergreen and popular spirit.
