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Thinking about Life
Our previous book, About Life, concerned modern biology. We used our present-day understanding of cells to ‘define’ the living state, providing a basis for exploring several general-interest topics: the origin of life, extraterrestrial life, intelligence, and the possibility that humans are unique. The ideas we proposed in About Life were intended as starting-points for debate – we did not claim them as ‘truth’ – but the information on which they were based is currently accepted as ‘scientific fact’. What does that mean? What is ‘scientific fact’ and why is it accepted? What is science – and is biology like other sciences such as physics (except in subject m- ter)? The book you are now reading investigates these questions – and some related ones. Like About Life, it may particularly interest a reader who wishes to change career to biology and its related subdisciplines. In line with a recommendation by the British Association for the Advancement of Science – that the public should be given fuller information about the nature of science – we present the concepts underpinning biology and a survey of its historical and philosophical basis.
Prison Writing
A collection of writing by people in prison and connected to prisons: creative and challenging - one of two special Waterside Press editions. 'A remarkable anthology which will interest everyone concerned with the fate of prisoners and anxious to see their conditions improved': Michael McMullan, Justice of the Peace. 'This fascinating and very readable collection of fact, fiction and verse is the fifteenth issue edited and produced by two probation officers from Sheffield. We are fortunate that they have found a new publisher in Waterside Press to continue giving prisoners (and others), an opportunity to do something wich all writers crave - find an audience to communicate their feelings and experiences... The contributors give deeply personal insights into the nature of their world and prove that imagination and talent are incapable of being destroyed if people are ready to develop them... This anthology deserves to be read... by everyone who is interested in new writers experimenting with the development of their talent. Each piece is different and compelling: David Underhill, The Magistrate.
Nuclear Matrix
Research on the nuclear matrix has grown enormously since Bereney and Coffey first reported its isolation and initial characterization in 1974. Since then, more than 1000 papers have been published on the subject by numerous workers around the world. This is the first book devoted to reviewing the major developments in this growing field. Key Features * The chapters cover a variety of topics, including: * Isolation of the nuclear matrix * Nuclear structure morphology in situ * Structural domains of the nuclear matrix and its components * Biochemistry and molecular biology of the matrix proteins and associated DNA and RNA * Functional properties associated with the nuclear matrix * DNA replication * Transcription * RNA splicing * Transcription regulation * Intranuclear and nucleocytoplasmic transport and targeting * Cell cycle regulation
International Review of Cytology
International Review of Cytology presents current advances and comprehensive reviews in cell biology--both plant and animal. Articles address structure and control of gene expression, nucleocytoplasmic interactions, control of cell development and differentiation, and cell transformation and growth. Authored by some of the foremost scientists in the field, each volume provides up-to-date information and directions for future research.
Metaphysics in the Age of Scientific Hegemony
This book consists of a series of essays which concern themselves with the persisting relevance of metaphysical speculation in our time. It delves into Hegel’s politics, the ethics of Confucius and Aristotle, the research of Leibniz, with its astonishing anticipations of modern ideas, Wittgenstein’s reflections on language, the meaning of music and art and a capital instance of a failed enquiry into life and mind from a scientific point of view. In all these instances, the focus is on the autonomous agency of the human being. Metaphysics as a philosophical discipline has long been under fire for its doctrinal presumptions, but never more so than under the hegemony of science. Yet, as the essays in this volume demonstrate, it remains an indispensable tool for thinkers in all areas of research in which the human creature is under the spotlight. That this involves a reversal of competences has not been seriously accepted—predominantly in terms of the gulf between autonomous agency and the mechanistic doxa under which science is compelled to operate. This volume seeks to put the torch on these discrepancies, where presuppositions end and understanding must take over.
The Medical Pioneers of Nineteenth Century Lancaster
Modern medicine in England as we know it today is chiefly the product of the scientific developments of the nineteenth century. These advances included improved sanitation, the acceptance of the germ theory of disease as a result of the emergence of microbiology, and the advent of painless and routine surgical procedures. How then did medicine evolve in Lancaster during the nineteenth century? The focus here is the history of medicine in Lancaster and a community of practice amongst a few medical professionals who shaped Lancaster’s medical landscape. The reader will be introduced to these remarkable medical men and their names will gradually become familiar. Many of these individuals were second and even third generation surgeons and physicians. Background to these pioneers, as well as their successes and failures, is sketched within the context of Lancaster’s socio-economic environment and growth as an industrial town. This volume also marks the main medical events in Lancaster, including the establishment of a Dispensary, which evolved into the Royal Lancaster Infirmary, the Public Health movement and the rise of the Asylums.
Biology
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Protein Conformation
Protein structure is the characteristic 3-dimensional shape of a protein, imposed upon it by the secondary and tertiary structure of the peptide chain. This stage in the structure of a protein describes the highest level of organisation in overall structure assumed by multimeric proteins (aggregates of more than one polypeptide chain). This is the fourth folding level of protein building. This new book presents the latest research in the field.
A Guide to the Scientific Career
A concise, easy-to-read source of essential tips and skills for writing research papers and career management In order to be truly successful in the biomedical professions, one must have excellent communication skills and networking abilities. Of equal importance is the possession of sufficient clinical knowledge, as well as a proficiency in conducting research and writing scientific papers. This unique and important book provides medical students and residents with the most commonly encountered topics in the academic and professional lifestyle, teaching them all of the practical nuances that are often only learned through experience. Written by a team of experienced professionals to help gu...
