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The basis for cell proliferation entails the control of key signalling and cell cycle regulators through transcriptional, translational, post-translational, genetic and epigenetic mechanisms. Many conceptual breakthroughs in cell regulation have derived from analyses of basic cell cycle mechanisms. This book presents research in the field.
A fundamental and groundbreaking reassessment of how we view and manage cancer When we think of the forces driving cancer, we don’t necessarily think of evolution. But evolution and cancer are closely linked because the historical processes that created life also created cancer. The Cheating Cell delves into this extraordinary relationship, and shows that by understanding cancer’s evolutionary origins, researchers can come up with more effective, revolutionary treatments. Athena Aktipis goes back billions of years to explore when unicellular forms became multicellular organisms. Within these bodies of cooperating cells, cheating ones arose, overusing resources and replicating out of cont...
Quando pensiamo alle forze che hanno dato vita al cancro non pensiamo all’evoluzione. In realtà le due cose sono strettamente connesse: il processo storico che ha creato la vita è il medesimo che crea il cancro. Questo saggio torna indietro a milioni di anni fa, al momento in cui le forme unicellulari diventarono organismi multicellulari, e fra quei corpi di cellule cooperanti emersero quelle che utilizzavano troppe risorse e si replicavano senza controllo. L’autrice mostra quanto l’evoluzione abbia spianato il campo per l’ubiquità del cancro, e perché continuerà a esistere finché esisterà la vita multicellulare. Tuttavia questo non significa che dobbiamo rinunciare a curarlo,...
One of PopSugar's Best Books of 2021 When her true-crime podcast becomes an overnight sensation, a young woman is pulled into the web of a case that may offer a surprising connection to her own sister's disappearance years earlier. It's been more than twenty years since Marti Reese's sister, Maggie, disappeared. Only eight-years-old at the time, Marti can't remember what happened, just that Maggie got into a car and never returned. After years of grief and countless false leads, Marti is coping as best she can: abandoning her marriage, drinking to forget, and documenting her never-ending search via a true-crime podcast. But when the podcast becomes an unexpected hit and Marti thinks she's fi...
The AACR Annual Meeting is a must-attend event for cancer researchers and the broader cancer community. This year's theme, "Delivering Cures Through Cancer Science," reinforces the inextricable link between research and advances in patient care. The theme will be evident throughout the meeting as the latest, most exciting discoveries are presented in every area of cancer research. There will be a number of presentations that include exciting new data from cutting-edge clinical trials as well as companion presentations that spotlight the science behind the trials and implications for delivering improved care to patients. This book contains abstracts 2697-5293 presented on April 19-20, 2016, at the AACR Annual Meeting.
Este livro reúne artigos científicos de professores, magistrados, membros do Ministério Público, advogados, colegas de trabalho e ex-alunos do Professor Rui Geraldo Camargo Viana. A coletânea tem como fio condutor um dos temas de predileção do homenageado: os direitos da personalidade. Com o advento da teoria dos direitos da personalidade, a concepção jurídica tradicional – exclusivamente patrimonial, migra da categoria histórico-conceitual do "ter" para o "ser". Por isso atualmente fala-se em "repersonalização" do direito civil. Cada artigo apresentado oferece a essência do assunto eleito, sem comprometimento da qualidade jurídica. Desejamos que a obra conduza o leitor a av...
The most-trusted film critic in America." --USA Today Roger Ebert actually likes movies. It's a refreshing trait in a critic, and not as prevalent as you'd expect." --Mick LaSalle, San Francisco Chronicle America's favorite movie critic assesses the year's films from Brokeback Mountain to Wallace and Gromit: The Curse of the Were-Rabbit. Roger Ebert's Movie Yearbook 2007 is perfect for film aficionados the world over. Roger Ebert's Movie Yearbook 2007 includes every review by Ebert written in the 30 months from January 2004 through June 2006-about 650 in all. Also included in the Yearbook, which is about 65 percent new every year, are: * Interviews with newsmakers such as Philip Seymour Hoffman, Terrence Howard, Stephen Spielberg, Ang Lee, and Heath Ledger, Nicolas Cage, and more. * All the new questions and answers from his Questions for the Movie Answer Man columns. * Daily film festival coverage from Cannes, Toronto, Sundance, and Telluride. *Essays on film issues and tributes to actors and directors who died during the year.