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The Handbook of Adult Language Disorders is the essential guide to the scientific and clinical tenets of aphasia study and treatment. It focuses on how language breaks down after focal brain damage, what patterns of impairment reveal about normal language, and how recovery can be optimally facilitated. It is unique in that it reviews studies from the major disciplines in which aphasia research is conducted—cognitive neuropsychology, linguistics, neurology, neuroimaging, and speech-language pathology—as they apply to each topic of language. For each language domain, there are chapters devoted to theory and models of the language task, the neural basis of the language task (focusing on rec...
Standard therapy for high grade glioma is a topic that is evolving, timely, and relevant. Guest Editors Isaac Yang, MD and Seunggu Han, MD have assembled a group of experts to highlight the latest updates on various forms of management of high grade glioma. Some of the articles included in this issue focus on Extent of Resection for Glioblastoma; Role of adjuvant radiation therapy; Survival benefit of the Temozolomide protocol; Alternative chemotherapeutic agents; The role of avastin; Radiology; Pseuodprogression and Treatment effect; Pathology; Medical Management; Management of insular gliomas; Use of motor mapping; GBM treatment with clinical trials for surgical resection; Clinical trials with immunotherapy; Clinical trials for small molecule inhibitors; Future role of CED for GBM treatment; Application of a vault nanoparticle therapy for GBM therapy; Management of high grade gliomas in pediatric populations; Targeting Glioma Stem Like Cells with a focus on CD 133; and Potential Role for STAT3 inhibitors in glioblastoma.
This book covers all aspects of awake craniotomy, including preoperative management, intraoperative handling, and postoperative follow-ups. It will be discussed preoperative preparedness, essential neurocognitive assessments, and how to provide a patient for cooperative operation step by step. Intraoperative requirements and appropriate neuro-monitoring will be pointed out along with surgical nuances accompany by helpful photographs. Finally, the postoperative management, how we should control the patient in the short-term and long-term, and what investigations are necessary postoperatively will be explained. This book will assist neurosurgeons in negotiating the steep learning curve involved in gaining the skills needed to perform awake surgery of brain tumors, which offers significant advantages in terms of avoidance of preventable neurological deficits besides obtaining optimal outcome. Indeed, primary audiences of this work are neurosurgeons, neurologists, neuroscientists, and neuro-anesthesiologists, and it will contain neuropsychiatry, neurosciences, neurology, neurosurgery, anesthesiology, and neurophysiologic contents.
This issue of Anesthesiology Clinics provides essential updates in neurosurgical anesthesia. Topics include anesthesia for endovascular neurosurgery; interventional neuroradiology; neuroimaging; anesthetic management of patients with acute stroke; perioperative management of pediatric patients; anesthetic neurotoxicity; airway management in neuroanesthesiology; anesthetic considerations for awake craniotomy for epilepsy; perioperative uses of trans cranial perfusion monitoring; monitoring and introaoperative management of elevated ICP and decompressive craniectomy; electrophysiologic monitoring in neurosurgery; traumatic brain injury; perioperative pain management in the neurosurgical patient; controversies in neurosciences critical care; sleep and mechanisms of anesthesia; and impacts on outcome after neuroanesthesia.
Neuroimaging in Neurogenic Communication Disorders provides a comprehensive review of cases utilizing neuroimaging in neurogenic communication disorders. Basic knowledge of neuroanatomy and medical conditions related to these speech and language disorders are discussed. Each case study includes information on neuroanatomy, case presentation, neuroimaging, differential diagnosis, and final diagnosis. This book is written for medical students, practitioners and researchers in neuroscience and speech language pathology. Neurogenic communication disorders are caused by damage to the central or peripheral nervous system. This damage can be caused by Parkinson's disease, stroke, dementia, traumatic brain injury, brain tumors, and other neurologic disorders and causes issues such as aphasia, dysarthria and apraxia. - Focuses on neuroimaging in acquired neurogenic communication disorders like apraxia, dysarthria and aphasia - Covers basic neuroanatomy as related to speech and pathology - Includes cases organized by anatomical entities involved in lesions
This volume reviews standard treatments for spinal dural arteriovenous fistulas, examining the anatomy of arteries and veins of the sylvian fissure, as well as microsurgical advances and the development of modern therapeutic strategies in intracranial meningiomas. The advances section presents a strategy for minimizing hearing loss after stereotactic radiosurgery for vestibular schwannomas, as well as a description of the mode of action and biology of ALA, including its interaction with tumor cells and the limits of this method. A dedicated chapter addresses the essential question of the limits (and merits) of various tractography techniques and of their importance for non-specialists, who may be tempted to use them uncritically. A further chapter examines molecular markers, which have become standard in neuropathological reports on intracranial tumors, reviewing the prognostic and predictive value of these modern molecular markers in gliomas. Additional chapters round out the coverage, offering a comprehensive overview of standard and advanced techniques.
A unique overview of the human language faculty at all levels of organization. Language is not only one of the most complex cognitive functions that we command, it is also the aspect of the mind that makes us uniquely human. Research suggests that the human brain exhibits a language readiness not found in the brains of other species. This volume brings together contributions from a range of fields to examine humans' language capacity from multiple perspectives, analyzing it at genetic, neurobiological, psychological, and linguistic levels. In recent decades, advances in computational modeling, neuroimaging, and genetic sequencing have made possible new approaches to the study of language, an...