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The essays in this two-volume anthology provide the reader with an overview of current Czech, Polish and Hungarian research in language, literature and meaning as well as some new perspectives on the major theoretical contributions of Roman Ingarden, Georg Lukács and Jan Mukarovský. For the most part, the emphasis is on Poetics and Literary Theory; however, in some of the essays the focus shifts to such related disciplines as Aesthetics, Linguistics and Semiotics. The heterogeneity of this collection reflects the broad spectrum of interests and approaches to problems of theory being pursued at present in Poland, Hungary and Czechoslovakia. Much of the work being done in these countries remains relatively unknown outside of Eastern Europe. This anthology is an attempt to rectify this situation and make better known the nature and extent of research which promises new insights into a whole range of phenomena in language, literature and culture.
Although best known for its role in heart disease, the sarcomere--the fundamental unit of muscle contraction--is also involved in skeletal muscle diseases. Chapters in The Sarcomere and Skeletal Muscle Disease provide an up-to-date review of diseases caused by mutated proteins in the different sub-compartments of the sarcomere, document the techniques currently being used to investigate the pathobiological bases of the diseases, which remain largely unknown, and discuss possible therapeutic options.
Photographer Guy Martin investigates the blurred lines between reality and fiction in Turkey.
Neurogenetics is a growing field, providing a clear link between clinical characteristics of phenotypes and exact molecular tests to reach a specific diagnosis. Neurogenetics for the Practitioner provides clinicians with a navigation tool to help diagnose and treat patients with neurological disorders using neurogenetics. The first section introduces the reader to an overview of genetic principles, including practical applications in relation to diagnosis and current limitations. Additional chapters highlight how to workup patients presenting with certain features including cerebral palsy/intellectual disability, congenital muscular dystrophy, cognitive decline/dementia, peripheral neuropathy, and paroxysmal disorder. The final section explores therapeutic strategies based on genetic interventions and genetic counselling options. Internationally contributed, this book will become the essential reference guide for neurologist. - Reviews genetic testing for diagnostic confirmation, including carrier testing and prenatal diagnosis - Explores various therapeutic strategies based on genetic interventions - Discusses when a neurologic problem may have an underlying genetic cause
Written by a leading expert in the area, this fourth edition continues to offer critical and comprehensive coverage of the four freedoms in a concise and user-friendly format, featuring engaging case studies and diagrams to explain the key areas of substantive EU law while maintaining authoritative, reliable content.
Vols. for 1964- have guides and journal lists.
The emergence of marine and freshwater toxins in geographical areas where they have never been reported before is a concern due to the considerable impact on (sea)food contamination, and consequently, on public health. Several groups of marine biotoxins, in particular tetrodotoxins, ciguatoxins, and palytoxins, are included among the relevant marine biotoxins that have recently emerged in several coastal areas. A similar situation has been observed in freshwater, where cyanobacterial toxins, such as microcystins, could end up in unexpected areas such as the estuaries where shellfish are cultivated. Climate change and the increased availability of nutrients have been considered as the key fac...