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This book reviews the state-of-the-art in stem-cell-based therapies for neurodegenerative diseases, and highlights advances in both animal models and clinical trials. It comprehensively discusses most neurodegenerative diseases, including such as Parkinson's, Alzheimer's and Huntington’s diseases, amyotrophic sclerosis, multiple sclerosis, muscular dystrophy and retinal degeneration, in which stem cells could potentially be used for therapy in the future. It also addresses the challenges and problems relating to the translation of stem-cell-based therapies into treatments. As such, the book will appeal to research scientists, physicians, graduate students, and medical professionals in the field of stem cells, neuroscience, neurology, neurorestoratology and major neurological disorders.
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Programmed cell death (PCD) is a genetically encoded, active process which results in the death of individual cells, tissues, or whole organs. PCD plays an essential role in plant development and defense, and occurs throughout a plant’s lifecycle from the death of the embryonic suspensor to leaf and floral organ senescence. In plant biology, PCD is a relatively new research area, however, as its fundamental importance is further recognized, publications in the area are beginning to increase significantly. The field currently has few foundational reference books and there is a critical need for books that summarizes recent findings in this important area. This book contains chapters written by several of the world’s leading researchers in PCD. This book will be invaluable for PhD or graduate students, or for scientists and researchers entering the field. Established researchers will also find this timely work useful as an up-to-date overview of this fascinating research area.
This book serves as a good starting point for anyone interested in the application of tissue engineering. It offers a colorful mix of topics, which explain the obstacles and possible solutions for TE applications. The first part covers the use of adult stem cells and their applications. The following chapters offer an insight into the development of a tailored biomaterial for organ replacement and highlight the importance of cell-biomaterial interaction. In summary, this book offers insights into a wide variety of cells, biomaterials, interfaces and applications of the next generation biotechnology, which is tissue engineering.
This book differs from others on name reactions in organic chemistry by focusing on their mechanisms. It covers over 300 classical as well as contemporary name reactions. Biographical sketches for the chemists who discovered or developed those name reactions have been included. Each reaction is delineated by its detailed step-by-step, electron-pushing mechanism, supplemented with the original and the latest references, especially review articles. This book contains major improvements over the previous edition and the subject index is significantly expanded.
Initially considered as a sub-class of ionic liquids, eutectic mixtures are formed by mixtures of low cost, often biodegradable Lewis or Bronsted acids and bases. Eutectic mixtures have gathered a growing scientific interest by the academic and industrial communities as they are interesting for many applications ranging from metal processing to biomass treatment or pharmaceuticals. This volume gathers contributions by some of the most active research groups in the world using eutectic mixtures for applications in separation, extraction or pharmaceutical and medical applications. The different contributions aim at a large overview of the field for these particular applications by reviewing literature data and presenting ground breaking research in the different fields.
This is one of the first books fully dedicated to the rapidly advancing and expanding research area of deep eutectic solvents. Written by the internationally recognized expert in solution chemistry, it supplies full information regarding preparation of these new eco-friendly solvents, their properties and applications. The current and potential applications of deep eutectic solvents as organic reaction media, catalytic system, in biomass processing, nanotechnology and metal finishing industry, as well as for extraction and separation are extensively discussed.This highly informative and carefully presented book will appeal to practicing chemists (organic chemists, polymer chemists, biochemists) as well as chemical engineers and environmental scientists.