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First multi-year cumulation covers six years: 1965-70.
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Sodium and Water Homeostasis
This book presents cutting edge methods that provide insights into the pathways by which salt and water traverse cell membranes and flow in an orchestrated fashion amongst the many compartments of the body. It focuses on a number of molecular, cellular and whole animal studies that involve multiple physiological systems and shows how the internal milieu is regulated by multifactorial gene regulation, molecular signaling, and cell and organ architecture. Topics covered include: water channels, the urinary concentrating mechanism, angiotensin, the endothelin system, miRNAs and MicroRNA in osmoregulation, desert-adapted mammals, the giraffe kidney, mosquito Malpighian tubules, and circadian rhythms. The book highlights how different approaches to explaining the same physiological processes greatly increase our understanding of these fundamental processes. Greater integration of comparative, evolutionary and genetic animal models in basic science and medical science will improve our overall grasp of the mechanisms of sodium and water balance.
Semiotics Continues to Astonish
Peirce's (1906) proposal that the universe as a whole, even if it does not consist exclusively of signs, is yet everywhere perfused with signs, is a thesis that better than any other sums up the life and work of Thomas A. Sebeok, "inventor" of semiotics as we know it today. Semiotics - the doctrine of signs - has a long and intriguing history that extends back well beyond the last century, two and a half millennia to Hippocrates of Cos. It ranges through the teachings of Augustine, Scholastic philosophy, the work of Peirce and Saussure. Yet a fully-fledged doctrine of signs, with many horizons for the future, was the result of Sebeok's work in the twentieth century. The massive influence of ...
