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Scientific research in different nations, particularly after World War II.
This text investigates advances in the field of sommites and integrates them into the accumulated knowledge of how sommites form and differentiate. Although the book focuses on the formation and patterning of somites it will encompass a broader life history of a somite. Topics include events attending gastrulation, which foreshadow somite formation, to the subsequent contributions that somites make to neighbouring regions such as musculature, limbs and axial skeleton. There is also a discussion of the origins of cells that eventually give rise to somites. This book brings together investigators from NATO and NATO partner countries who are employing both classical and molecular approaches to the analysis of somitogenesis.
In this fascinating book, one of the world's most eminent developmental biologists discusses some of the exciting new insights into how genes control development. Walter Gehring describes in vivid detail his essential contributions to the landmark discovery of the homeobox, a characteristic DNA segment found in the genes of all higher organisms from the fruitfly to humans, and he explains how this has provided the key to our modern understanding of development and evolution. The book thus becomes not only a lucid discussion of genetics but also an engaging description of the art of scientific investigation. Gehring begins his story by looking at the work of the many researchers who laid the ...
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In this masterful account, a historian of science surveys the molecular biology revolution, its origin and continuing impact. Since the 1930s, a molecular vision has been transforming biology. Michel Morange provides an incisive and overarching history of this transformation, from the early attempts to explain organisms by the structure of their chemical components, to the birth and consolidation of genetics, to the latest technologies and discoveries enabled by the new science of life. Morange revisits A History of Molecular Biology and offers new insights from the past twenty years into his analysis. The Black Box of Biology shows that what led to the incredible transformation of biology w...
Proceedings of the NATO Advanced Research Workshop on Vectors for Transfer and Expression of Genes held in Wilsede, FRG, October 21-24, 1988 on the Occasion of the 40th Anniversary of the Heinrich-Pette-Institut fürExperimentelle Virologie u. Immunologie an der Univ. Hamburg
This book provides a comprehensive view of research in lens developmental biology, emphasising technical and molecular breakthroughs. Elucidation of the mechanisms that govern lens development has enabled us to understand how the normal lens forms and how developmental processes are involved in the maintenance of its normal structure, function and growth throughout life. This knowledge is fundamental to our understanding of many lens disorders. The ocular lens has also become a model for understanding the developmental biology of more complex organ systems. In this 2004 book, leading experts in lens cell biology and development discuss lens evolution, induction, morphology, the regulation of the lens cell cycle and fiber cell differentiation, as well as lens regeneration. This book is an authoritative treatment of the subject that will serve as a reference for graduate students and research scientists in developmental biology and in the visual sciences, as well as for ophthalmologists.
This book provides the first comprehensive historical account of the evolution of scientific traditions in astronomy, astrophysics, and the space sciences within the Max Planck Society. Structured with in-depth archival research, interviews with protagonists, unpublished photographs, and an extensive bibliography, it follows a unique history: from the post-war relaunch of physical sciences in West Germany, to the spectacular developments and successes of cosmic sciences in the second half of the 20th century, up to the emergence of multi-messenger astronomy. It reveals how the Society acquired national and international acclaim in becoming one of the world’s most productive research organizations in these fields.
Current Topics in Developmental Biology
Molecular Mechanisms in Cellular Growth and Differentiation describes the cellular differentiation and development. It emphasizes the pattern formation, specifically the genesis of spatial relationships, among the parts of a vertebrate or invertebrate organism, embryonic or adult. Organized into five parts, this book deals with the major steps leading from growth factor-receptor interactions, through transduction and modulation mechanisms, to proliferative response. It also discusses the relation of growth factors and their receptors to oncogenes and to protooncogenes. It also elucidates the roles of growth factors and receptors in cell differentiation and development, particularly, in pattern formation. The homeotic systems regulated intracellularly and the two differentiation systems thought to involve sequence-specific DNA-binding proteins in conjunction with small molecules are also explored.