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This volume compiles the perspectives of a multi-author team examining the entire spectrum of burn reconstruction and long-term treatment. Individual chapters cover basic aspects of wound healing and scarring, and those of plastic surgery relating to tissue rearrangement and the use of flaps, as well as the long-term use of skin and skin substitutes. Furthermore, topics such as rehabilitation and scar management are addressed in detail. This part provides detailed reconstruction guidelines divided by anatomic region (e.g. face, hands,...), as well as aspects of future trends and prospects in burn reconstruction, among which are e.g. allotransplantation and bionics.
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This volume covers the entire spectrum of acute burn treatment. Individual chapters deal with basic aspects of different burn mechanisms as well as the acute care of burn patients. Pre-hospital management, critical care and basic concepts of burn surgery related to the acute phase, as well as the use of skin and skin substitutes in early stages of therapy are addressed in this volume. Chapters on supportive therapies such as optimizing nutrition and fluid homeostasis, infection control and treatment, respiratory support and pain management complete the comprehensive approach to the patient in this early stage of treatment, while chapters on epidemiology, prevention and disaster management enable the reader to evaluate the given information in a broader context.
The skin is the largest human organ system. Loss of skin integrity due to injury or illness results in a substantial physiologic imbalance and ultimately in severe disability or death. The most common cause of significant skin loss is thermal injury, followed by trauma and chronic ulcerations. Over the past decades extraordinary advances have been made in the understanding of cellular and molecular processes of wound healing and the pathobiology of chronic wounds. This knowledge has led to wound care innovations that facilitate more rapid closure of wounds with better functional and aesthetic outcome. A sensible and resource-saving utilization of these innovative technologies requires a broad knowledge of these processes and innovations. This book intends to give an overview about today's wound care developments in tissue engineering and skin replacement. It presents a variety of indications and diversities of clinical applications to help the surgeon select a specific procedure for each clinical situation.
Although glycoproteins and proteoglycans have been a subject of re search for many years, it is only during the last five or so years that they have aroused the interest of a very broad cross section of investigators in the biological sciences. The reason for this expanded interest in these molecules is simple: not only are glycoproteins and proteoglycans ubiq uitous, but many are molecules with well-defined and important biological functions. The list of molecules that fall into this category grows daily; interferon, immunoglobulins, certain hormones, many cell surface recep tors, and viral coat proteins are but a few examples. Thus, investigators with interests as diverse as viral replicat...
A comprehensive survey of the topic, ranging from basic molecular research to clinical applications. Critical reviews by leading experts in each field summarize the state of knowledge and discuss the anticipated benefits of novel approaches and strategies. These include the impact of modern analysis techniques on glycobiology, the use of synthetic neoglycoproteins, or the clinical consequences of new insights into the physiological role of lectins and glycoconjugates in pathology, oncology, immunity, neuroscience and reproduction medicine. Throughout, the aim is to separate realistic applications from mere hopes.
Features high-quality illustrations and new surgical techniques for treatment of injured, diseased, or deformed hands.
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