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Biochemical Adaptation
This book discusses biochemical adaptation to environments from freezing polar oceans to boiling hot springs, and under hydrostatic pressures up to 1,000 times that at sea level. Originally published in 1984. The Princeton Legacy Library uses the latest print-on-demand technology to again make available previously out-of-print books from the distinguished backlist of Princeton University Press. These editions preserve the original texts of these important books while presenting them in durable paperback and hardcover editions. The goal of the Princeton Legacy Library is to vastly increase access to the rich scholarly heritage found in the thousands of books published by Princeton University Press since its founding in 1905.
Muscles as Molecular and Metabolic Machines
First published in 1994, this book explores the paradigm of muscles as molecular and metabolic machines in which all structures and functions are exquisitely integrated and matched to each other. The analysis begins with a standard reductionist approach-reviewing the integrated machine parts. The key working components of the complete muscle machine are proteins (soluble, organelle, or membrane localized), and a conservative count indicates that today more than 100 such machine parts are known, essentially all occurring as cell specific isoforms. Random assortment of these machine parts or protein isoforms could generate an astronomical number of "muscle machines" and an equally enormous num...
Surviving Hypoxia
Surviving Hypoxia: Mechanisms of Control and Adaptation is a synthesis of findings and thoughts concerning hypoxia. The thermodynamics of hypoxia are discussed in detail, including acid-base balance and self-pollution resulting from the accumulation of anaerobic end-products. The book focuses on descriptions and discussions of common facets, contrasting solutions in a variety of physiological hypoxia defense strategies, including those shown by plants, invertebrates, and vertebrates. Special treatment is given to the distinctive problems that hypoxia presents to vulnerable organs such as the kidney, liver, and brain. It also addresses pathological events in addition to protective mechanisms. Clinical implications of basic research are examined in the book, which provides new insights into underlying pathological processes occuring in hypoxic-induced organ failure and indicates new paths for successful clinical intervention. Surviving Hypoxia: Mechanisms of Control and Adaptation is an excellent reference for all researchers interested in the physiological effects of hypoxia, underlying pathological events, and protective mechanisms.
Living Without Oxygen
Innumerable clinical problems have as their basis some derangement in oxygen-dependent metabolism. To explore mechanisms of adjusting to oxygen limitation, Living without Oxygen presents a bestiary of exotic anaerobes that illuminate elements of metabolic biochemistry only dimly seen in studies using standard experimental animals. With their exaggerated anaerobic capabilities, Hochachka's diving mammals, airbreathing fishes, and hypoxia-adapted lower vertebrates allow a detailed assessment of what can and what cannot be adjusted in the process of extending hypoxia tolerance. The book places the enzymatic and biochemical machinery firmly in the biological context and assumes only a modest familiarity with bioenergetics and metabolic biochemistry. The author's clear prose should make this technical presentation pleasantly unintimidating for any physiologist, biochemist, or clinical investigator. The insights of his unique approach make Living without Oxygen essential reading.
Phylogenetic and Biochemical Perspectives
This new series on The Biochemistry and Molecular Biology of Fishes grew out of the demand for state-of-the-art review articles in a rapidly expanding field of research. Up to the present, most research literature on biochemistry involved rats and humans, but new breakthroughs in the piscine setting have indicated that the field is ready for a review series of its own. Because of funding and experimental availability restrictions, most research in the field has dealt with fish and insects. Within the insect field, comparative biochemistry and comparative physiology have proceeded along independent paths as opposed to the piscine field, where the tendency has been for the latter to envelop the former.This volume sets out to make comparative biochemistry and comparative physiology independent of each other within the piscine setting, another important rationale for this review series as well as detailing the phylogenetic evolution of fishes. The goal of the series is to provide researchers and students with an appropriate balance between experimental results and theoretical concepts.
Mollusca
The Mollusca, Volume 1: Metabolic Biochemistry and Molecular Biomechanics provides information pertinent to the advances in the traditional areas of biochemistry and in other developed areas that have become a part of molluskan biochemistry. This book discusses the developments in the various aspects of molecular biomechanics and environmental biochemistry. Organized into 11 chapters, this volume begins with an overview of the phylum Mollusca. This text then provides information about the general features of the main classes and their evolution, the anatomical organization of mollusks, and a classification of the primary taxonomic groups of mollusks. Other chapters consider the functional mechanical properties of two protein rubbers found in molluskan connective tissues. This book discusses as well the mechanical properties of molluskan mucins. The final chapter deals with the significance of quinone tanning in mollusks. This book is a valuable resource for researchers of the Mollusca and other phyla, as well as to teachers and qualified graduate students. Biochemists and physiologists will also find this book useful.
The Physiology of Polar Fishes
Devoted to fishes of high latitudes (Arctic and Antarctic). This book includes themes such as: the uniqueness of the physiology of fishes that live in cold polar environments, an analysis of physiological patterns exemplified by fishes that live poles apart, and how fishes differ from fishes living in more temperate and tropical habitats.
Metabolic Arrest and the Control of Biological Time
What mechanisms turn down (or off) cell metabolism and other cell functions? How does an animal such as an opossum know when to activate mechanisms for slowing or stopping tissue and organ functions? These capabilities raise important questions, which Hochachka and Guppy explore in this seminal new book. This is a pioneering book of great use to biomedical/clinical researchers and to biologists, biochemists, and physiologists generally.
Citizen Science
Citizen science enlists members of the public to make and record useful observations, such as counting birds in their backyards, watching for the first budding leaf in spring, or measuring local snowfall. The large numbers of volunteers who participate in projects such as Project FeederWatch or Project BudBurst collect valuable research data, which, when pooled together, create an enormous body of scientific data on a vast geographic scale. In return, such projects aim to increase participants' connections to science, place, and nature, while supporting science literacy and environmental stewardship. In Citizen Science, experts from a variety of disciplines—including scientists and educati...
Invertebrate Histology
The first comprehensive reference to invertebrate histology Invertebrate Histology is a groundbreaking text that offers a comprehensive review of histology in invertebrates. Designed for use by anyone studying, diagnosing, or researching invertebrates, the book covers all major taxonomic groups with details of the histologic features, with color photographs and drawings that clearly demonstrate gross anatomy and histology. The authors, who are each experts in the histology of their respective taxa, bring together the most recent information on the topic into a single, complete volume. An accessible resource, each chapter focuses on a single taxonomic group with salient gross and histologic f...
