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Advances in Clinical Chemistry and Laboratory Medicine
This volume comprises the invited plenary lectures and contributed papers presented at the WorldMedLab and the EuroMedLab in Berlin, May 2011 with more than 5.000 participants. The contributions in this volume provide a valuable and wide-ranging overview of current research in Laboratory Medicine and cognate disciplines. Special focus is given to Aging Society (neurological diseases), Tumors, Organ specific dysfunctions and Future of Laboratory Medicine.
Microbial Host-interaction
Most indigenous microbes occur in the intestinal tract, and their interactions with the host are largely unknown. Current understanding of host-microbe interactions links early microbial contact to the origin of disease, a theory that has its roots in the hygiene hypothesis. Modern life style appears to deprive the infant of conditions that provide adequate anti-inflammatory or tolerogenic stimuli upon antigen encounter. Thus, maturational signals from the environment and the diet are insufficient to adequately shape the immune system. This publication deals with the relationship between the gut microbiota as well as altered pattern of early microbial contact and the origin of human disease. New aspects of the original hygiene hypothesis are discussed in relation to disorders spanning from allergy and autoimmunity to obesity.The results presented suggest that all these disorders may be linked to aberrant antigen absorption and immune responses associated with dysfunction of mucosal defense. Researchers, clinicians and students interested in the interaction of the host with indigenous gut bacteria and the consequences for human health will find this publication of utmost interest.
Immune maturation and modulation in childhood allergies
The prevalence of allergic diseases has in the past century increased among children in affluent societies. Underlying causes are incompletely disentangled, but decreased diversity in environmental and microbial exposures could drive allergy development. Allergic individuals possess imbalanced immune responses, skewed in favour of Th2 cells along with lesser Th1 and Treg responses. As allergy development early in life increases the risk of developing further allergic manifestations later, early prevention is key. Thus, interventions in pregnancy, early life and childhood may modulate immunity towards tolerance, although underpinnings of immune maturation and modulation in allergy prevention ...
Allergy Frontiers:Epigenetics, Allergens and Risk Factors
When I entered the field of allergy in the early 1970s, the standard textbook was a few hundred pages, and the specialty was so compact that texts were often authored entirely by a single individual and were never larger than one volume. Compare this with Allergy Frontiers: Epigenetics, Allergens, and Risk Factors, the present s- volume text with well over 150 contributors from throughout the world. This book captures the explosive growth of our specialty since the single-author textbooks referred to above. The unprecedented format of this work lies in its meticulous attention to detail yet comprehensive scope. For example, great detail is seen in manuscripts dealing with topics such as “E...
Management in der Ergotherapie
Die anstehenden Veränderungen im Gesundheitswesen bringen auch für die Berufsgruppe der ErgotherapeutInnen neue Aufgabenfelder und Herausforderungen mit sich. ErgotherapeutInnen nehmen immer mehr Managementaufgaben wahr und arbeiten in entsprechenden Leitungspositionen. Management in der Ergotherapie beschreibt neue konkrete Aufgabenfelder für Führungskräfte und zeigt Möglichkeiten der Qualifizierung im Managementbereich auf. Es richtet sich gezielt an Leitungskräfte, die ihre Aufgaben reflektierend, aber auch unter dem Aspekt neuer Gestaltungsmöglichkeiten betrachten. Es wendet sich aber auch an diejenigen, die einen Überblick und Einblick in Themen des Managements aus Sicht der Ergotherapie erhalten wollen: z.B. Controlling, Qualitätsmanagement, Öffentlichkeitsarbeit, Projektmanagement. Damit können sie die richtigen Entscheidungen für die eigene berufliche Entwicklung treffen. Das Buch ist als Lehrbuch für Aus-, Fort- und Weiterbildung konzipiert und auch für das Selbststudium geeignet.
Allergy, Immunity and Tolerance in Early Childhood
Allergy, Immunity and Tolerance in Early Childhood: The First Steps of the Atopic March provides valuable insights on the atopic diseases, including asthma, allergic rhinitis, atopic dermatitis, and food allergies, which have developed into major health problems in most parts of the world. As the natural history of these chronic diseases has been extensively studied, including their major genetic, environmental, and lifestyle determinants and potential protective factors, the book presents tactics on how pediatric allergists can provide early intervention. In addition, the book unites key, global experts in the field who summarize their collective, and current, knowledge of the early stage o...
Soot Formation in Combustion
Soot Formation in Combustion represents an up-to-date overview. The contributions trace back to the 1991 Heidelberg symposium entitled "Mechanism and Models of Soot Formation" and have all been reedited by Prof. Bockhorn in close contact with the original authors. The book gives an easy introduction to the field for newcomers, and provides detailed treatments for the specialists. The following list of contents illustrates the topics under review:
Choice of Law in Copyright and Related Rights
Nobody denies that the traditional territorial approach to copyright and other intellectual property rights has come under pressure. Yet it persists. Faced with the need to determine the applicable law in cross-border cases, lawyers everywhere wrestle with the implications of the territorial nature of copyright and related rights. In this book Mireille van Eechoud clears the way to the formulation of conflict rules that reflect the purpose of copyright law- to protect creators and stimulate the production and use of information- without reverting to old-fashioned notions of territoriality. She shows how the applicable law can be determined for four distinct legal avenues of intellectual prop...
