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Re-inventing Drug Development
The biopharmaceutical industry has entered an era of unprecedented change and challenge, characterized by increasing pricing pressures, rising rates of attrition in the product development lifecycle, and decreasing scientific innovation. The most successful products are losing patent protection, and pipelines have been unable to fill the gap. This
Industrialization of Drug Discovery
The drug discovery and development process is getting longer, more expensive, and no better. The industry suffers from the same clinical attrition and safety-related market withdrawal rates today as it did 20 years ago. Industrialization of Drug Discovery: From Target Selection Through Lead Optimization scrutinizes these problems in detail, contras
Econometrics
The most authoritative and up-to-date core econometrics textbook available Econometrics is the quantitative language of economic theory, analysis, and empirical work, and it has become a cornerstone of graduate economics programs. Econometrics provides graduate and PhD students with an essential introduction to this foundational subject in economics and serves as an invaluable reference for researchers and practitioners. This comprehensive textbook teaches fundamental concepts, emphasizes modern, real-world applications, and gives students an intuitive understanding of econometrics. Covers the full breadth of econometric theory and methods with mathematical rigor while emphasizing intuitive ...
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Drug Safety Data: How to Analyze, Summarize and Interpret to Determine Risk
Drug Safety Data: How to Analyze, Summarize and Interpret to Determine Risk was selected for The First Clinical Research Bookshelf - Essential reading for clinical research professionals by the Journal of Clinical Research Best Practices. Drug Safety Data: How to Analyze, Summarize and Interpret to Determine Risk provides drug safety/pharmacovogilance professionals, pharmaceutical and clinical research scientists, statisticians, programmers, medical writers, and technicians with an accessible, practical framework for the analysis, summary and interpretation of drug safety data. The only guide of its kind, Drug Safety Data: How to Analyze, Summarize and Interpret to Determine Risk is an inval...
The Incredible Unlikeliness of Being: Evolution and the Making of Us
"From your brain to your fingertips, you emerge from her book entertained and with a deeper understanding of yourself" --Richard Dawkins Alice Roberts takes you on the most incredible journey, revealing your path from a single cell to a complex embryo to a living, breathing, thinking person. It's a story that connects us with our distant ancestors and an extraordinary, unlikely chain of events that shaped human development and left a mark on all of us. Alice Roberts uses the latest research to uncover the evolutionary history hidden in all of us, from the secrets found only in our embryos and genes - including why as embroyos we have what look like gills - to those visible in your anatomy. This is a tale of discovery, exploring why and how we have developed as we have. This is your story, told as never before.
High & Low
Readins in high & low
Disconnecting the Dots
Questioning actions taken by American intelligence agencies prior to 9/11, this investigation charges that intelligence officials repeatedly and deliberately withheld information from the FBI, thereby allowing hijackers to attack the World Trade Center and the Pentagon. Pinpointing individuals associated with Alec Station, the CIA’s Osama bin Laden unit, as primarily responsible for many of the intelligence failures, this account analyzes the circumstances in which critical intelligence information was kept from FBI investigators in the wider context of the CIA’s operations against al-Qaeda, concluding that the information was intentionally omitted in order to allow an al-Qaeda attack to go forward against the United States. The book also looks at the findings of the four main 9/11 investigations, claiming they omitted key facts and were blind to the purposefulness of the wrongdoing they investigated. Additionally, it asserts that Alec Station’s chief was involved in key post-9/11 events and further intelligence failures, including the failure to capture Osama bin Laden at Tora Bora and the CIA's rendition and torture program.
Probability and Statistics for Economists
A comprehensive and up-to-date introduction to the mathematics that all economics students need to know Probability theory is the quantitative language used to handle uncertainty and is the foundation of modern statistics. Probability and Statistics for Economists provides graduate and PhD students with an essential introduction to mathematical probability and statistical theory, which are the basis of the methods used in econometrics. This incisive textbook teaches fundamental concepts, emphasizes modern, real-world applications, and gives students an intuitive understanding of the mathematics that every economist needs to know. Covers probability and statistics with mathematical rigor whil...
