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Modern African Wars (1)
The Rhodesian War of 1965–80 is the battle for control of present day Zimbabwe. The former British colony of Southern Rhodesia rejected British moves towards majority rule and on 11 November 1965 the Rhodesian Prime Minister Ian Smith announced his country's Unilateral Declaration of Independence from Great Britain. That act sparked a series of violent encounters between the traditional colonial army and the African guerilla insurgents of the Patriotic Front. This book examines the successes and failures of the counter-insurgency campaign of Smith's security forces and the eventual bloody birth of a modern African nation.
Immunotoxicology And Immunopharmacology
The second edition of this text has been revised and refocused to reflect the transformation of immunotoxicology from a subdiscipline of toxicology to an independent area of research that can best be described as "environmental immunology." New chapters discuss the role of immune mediators in liver, lung, and skin toxicity, in regulating chemical- metabolizing enzymes, and in the immunosuppression produced by ultraviolet light. More emphasis is placed on the clinical consequences of immunotoxicity, as well as the interpretation of experimental data for predicting, human health risk.; The second edition is divided into three major sections: immunosuppression, autoimmunity, and hypersensitivity. This new organization of the text allows for a more thorough treatment of these phenomena, with greater attention to test methods, theoretical considerations, and clinical implications. The book includes many chapters on specific environmental agents, therapeutic drugs, biological agents, and drugs of abuse, as well as on immune-mediated toxicity in specific organ systems.
Winning Wars amongst the People
Since the end of World War II a paradigm shift has occurred in armed conflict. Asymmetric, or fourth-generation warfareùthe challenge of nonstate belligerents to the authority and power of the stateùhas become the dominant form of conflict, while interstate conventional war has become an increasingly irrelevant instrument of statecraft. In asymmetric conflicts the enemy is often a fellow citizen with a different vision for the future of the countryùwaging war among the people, maneuvering on the borderlines between parliamentary politics, street politics, criminal activity, and combat operations. Winning Wars amongst the People analyzes the special circumstances of asymmetric conflicts in...
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Alternative Toxicological Methods
Bringing together the recent and relevant contributions of over 125 scientists from industry, government, and academia in North America and Western Europe, Alternative Toxicological Methods explores the development and validation of replacement, reduction, and refinement alternatives (the 3Rs) to animal testing. Internationally recognized scientist
Fighting for Time
This military study examines the evolution of the Rhodesian armed services during the complex conflicts of the Cold War era. Through the 1960s and 1970s, Africa endured a series of conflicts involving Rhodesia, South Africa, and Portugal in conflict with the Frontline States. The Cold War brought outside influences, including American interest at the diplomatic, economic, and social level. In Fighting for Time, military historian Charles D. Melson sheds new light on this complex and consequential period through analysis of the Rhodesian military. Drawing on a wealth of primary sources, Melson examines the Rhodesian military’s evolution into a special operations force conducting intelligenc...
Progress in the Reduction, Refinement, and Replacement of Animal Experimentation
Hardbound. New legislation enacted in many countries and regions of the world during the 1980s requires that laboratory animal use be reduced, refined and replaced wherever possible, for ethical and scientific reasons, in line with the Three Rs concept put forward by W.M.S. Russell and R.L. Bnurch in 1958, in The Principles of Humane Experimental Technique. This Congress provided an opportunity for a celebration of the 40th anniversary of the publication of this book, and for a coming together of many of those who are actively pursuing the implementation of the Three Rs in the interests of good science and humane science.Current uses and future prospects for the use of laboratory animal procedures and non-animal methods in the biomedical sciences are considered in five themes: the development of replacement alternative methods; the validation and regulatory acceptance of alternative test methods; reduction alternatives and the testi
Endocrine Disrupting Chemicals
Long-term environmental effects of chemical exposure have long been of concern and, more recently, chemicals which cause changes to the sexual development of exposed organisms have been identified. It is thought that low-level exposure to a wide range of chemicals may be affecting endocrine function, leading to a reduction in fertility and an increase in reproductive cancers. Endocrine Disrupting Chemicals reviews the scientific evidence and attempts to put the subject into context. Along with an overview of the issue, there is discussion of the specialised aspects in relation to wildlife; environmental oestrogens and male reproduction; and naturally occurring oestrogenic substances. With contributions from representatives of the Medical Research Council's Institute for Environment and Health and the US Environmental Protection Agency, the articles provide a comprehensive and detailed review of current issues. This book will be of interest to a wide readership, including industrial and environmental scientists, managers and policy makers.
