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Natural product chemistry has undergone an explosive growth during the latter half of the current century. This has been brought about by a number of factors. One of these has been the growing number of sub stances from natural sources which display interesting pharmacological activities. These include antibiotics, anti-tumor agents, immunostimu lants, drugs affecting the cardiovascular and central nervous systems, analgesics etc. Another factor has been the improvements made in the technology of isolation processes which includes the development of such techniques as high pressure liquid chromatography which has al lowed the rapid isolation of substances which were previously diffi cult to ...
S2Pokeweed, a plant abundant in Appalachia, exhibits some chemical similarities to a related species that has shown molluscicidal properties. Because this suggests that pokeweed, Phytolacca americana L. (P. decandra L.), has potential for controlling fresh-water snails, we have compiled this report of its chemical composition, uses, propagation methods, and other potentially useful species of the genus Phytolacca. The related species, Phytolacca dodencandra L'Her, was found to be the source of a molluscicide, which could pIay an important role in control of bilharziasis, a parasitic disease of humans widespread in Puerto Rico, Africa, and other tropical areas (22). Dead snails and small fish...