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Biology of Freedom
This groundbreaking book delivers a much needed bridge between the neurosciences and psychoanalysis. Freud hoped that the neurosciences would offer support for his psychoanalysis theories at some point in the future: both disciplines, after all, agree that experience leaves traces in the mind. But even today, as we enter the twenty-first century, all too many scientists and analysts maintain that each side has wholly different models of the origin and nature of those traces. What constitutes human experience, how does this experience shape us, and how, if at all, do we change our lives? Psychoanalysis and the neurosciences have failed to communicate about these questions, when they have not been frankly antagonistic. But, in Biology of Freedom, Francois Ansermet and Pierre Magistretti are at last breaking new ground. This fully illustrated account, rigorous yet lucid and entirely accessible, shows how the plasticity of the brain's neural network allows for successive inscriptions, transcriptions, and retranscriptions of experience, leading to the constitution of an inner reality, an unconscious psychic life unique to each individual.
Biology of Freedom
Freud hoped that the neurosciences would offer support for his psychoanalysis theories at some point in the future: both disciplines, after all, agree that experience leaves traces in the mind. This book delivers a bridge between the neurosciences and psychoanalysis.
Ammon's Horn, or The Mystery of the Brain
Five cutting-edge scientists compete for $100 million and control of a new institute dedicated to eradicating Alzheimer’s in this edifying, Da Vinci Code-esque thriller. Spurred by his wife’s Alzheimer’s diagnosis and disenchanted with the slow progress in finding a cure, a rich Swiss businessman launches a contest for promising young neuroscientists who can think “outside the box.” Chosen for their scientific excellence and originality, they must travel throughout Europe in search of the answers to five fiendishly difficult riddles, each combining an enigmatic neuroscientific question with a geographical and historical challenge. As their personal stories unfold, the competitors s...
Glial Man
Glial cells play an essential role in initiating and controlling our behaviours, playing a major role in communication between brain cells. They share certain properties with neurons, including the ability to use information from the environment to formulate behaviors. Understanding these cells is key to explaining human movement, emotion, and thoughts. Moreover, glial cells provide a panoply of new therapeutic targets for the treatment of neuropsychiatric disorders. This book is the 'brain' child of two scientist physicians: Pierre Magistretti, a leading expert in cerebral metabolism and glial cell biology, and Yves Agid, an expert in the treatment of nervous system diseases and a researcher in the field of neurodegenerative diseases. This book provides many examples of the decisive role glial cells play in the functioning of the human brain, as well as in neurological and psychiatric pathologies. The result is a revolution in our understanding of the brain and a beacon of hope in the treatment of neuropsychiatric disorders.
Neuropsychopharmacology
Thoroughly updated and completely reorganized for a sharper clinical focus, the Fifth Edition of this world-renowned classic synthesizes the latest advances in basic neurobiology, biological psychiatry, and clinical neuropsychopharmacology. The book establishes a critical bridge connecting new discoveries in molecular and cellular biology, genetics, and neuroimaging with the etiology, diagnosis, and treatment of all neuropsychiatric disorders. Nine sections focus on specific groups of disorders, covering clinical course, genetics, neurobiology, neuroimaging, and current and emerging therapeutics. Four sections cover neurotransmitter and signal transduction, emerging methods in molecular biology and genetics, emerging imaging technologies and their psychiatric applications, and drug discovery and evaluation. Compatibility: BlackBerry(R) OS 4.1 or Higher / iPhone/iPod Touch 2.0 or Higher /Palm OS 3.5 or higher / Palm Pre Classic / Symbian S60, 3rd edition (Nokia) / Windows Mobile(TM) Pocket PC (all versions) / Windows Mobile Smartphone / Windows 98SE/2000/ME/XP/Vista/Tablet PC
Biology of Freedom
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Memory Reconsolidation
Memory traces can become labile when retrieved. This has intrigued not only neuroscientists, psychologists, and cognitive scientists but also clinicians who work with memories to treat psychopathologies, such as psychotherapists and psychoanalysts. Psychotherapists and psychoanalysts question whether the treatments based on re-evoking memories engage reconsolidation and how treatments may work and be effective with reconsolidation processes. However, reconsolidation may not easily occur in older or very strong, consolidated memories, which are, in fact, those deeply rooted in most maladaptive behaviors, and most animal reconsolidation studies have been done on memories that are only days old. Hence, the questions deepen into many more complex layers, asking the following: How are memories formed and retrieved and in part become unconscious? How does retrieval in a therapeutic setting change those traces? Here, we propose some hypotheses based on neuroscientific knowledge to begin explaining the bases of Freudian unconscious and speculate on how memory traces and Freudian unconscious intersect.
Brain Plasticity
Proceedings of the Conference on Recent Advances in Neurobiology: Plasticity and Regeneration held in St. Vincent, Italy, October 9-11 1995
Glycolysis at 75: Is it Time to Tweak the First Elucidated Metabolic Pathway in History?
Glycolysis, the pathway of enzymatic reactions responsible for the breakdown of glucose into two trioses and further into pyruvate or lactate, was elucidated in 1940. For more than seven decades, it has been taught precisely the way its sequence was proposed by Embden, Meyerhof and Parnas. Accordingly, two outcomes of this pathway were proposed, an aerobic glycolysis, with pyruvate as its final product, and an anaerobic glycolysis, identical to the aerobic one, except for an additional reaction, where pyruvate is reduced to lactate. Several studies in the 1980s have shown that both muscle and brain tissues can oxidize and utilize lactate as an energy substrate, challenging this monocarboxyla...
