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Radiotherapy (RT) is a cornerstone of cancer treatment, being routinely used for approximately half of cancer patients in high-income countries. Despite the extensive use of RT for over 60 years, its toxicity on normal tissues often limits the treatment of radioresistant tumors and is responsible for significant decrease in patient’s quality of life. However, it was recently established that ultra-high dose rate (UHDR) irradiation induces significantly less normal tissues toxicities, while keeping similar antitumor effect compared to conventional dose rate irradiation. This so called “FLASH Effect" was demonstrated in vivo on different animal models and different organs by delivering the total amount of radiation dose in a very short time ( usually <200 ms), with average dose rates above 40 Gy/s and with different particles including electrons, protons and photons.
This volume will describe recent progress and future directions in radiation oncology and biology research, focusing on strategies designed to improve disease control and reduce the risk of long-term adverse effects on patients. As more and more patients are becoming long-term survivors, this strategy will become increasingly important--in radiation oncology and throughout the field of oncology.
The first clinical book on the hottest topic in radiation oncology, this timely teaching text offers step-by-step guidance in use of IMRT for cancers at each subsite of the head and neck. The book's high-end content gives readers the clinical decision-making expertise and technical proficiency to incorporate this state-of-the-art radiation treatment technique into practice. Unique to this text is the site-specific instruction on target determination and delineation, to ensure adequate treatment of the tumor target while sparing adjacent normal tissue. More than 250 detailed full-color and black-and-white illustrations clarify each step in clinical implementations of head and neck cancer trea...
Details technology associated with radiation oncology, emphasizing design of all equipment allied with radiation treatment. Describes procedures required to implement equipment in clinical service, covering needs assessment, purchase, acceptance, and commissioning, and explains quality assurance issues. Also addresses less common and evolving technologies. For medical physicists and radiation oncologists, as well as radiation therapists, dosimetrists, and engineering technologists. Includes bandw medical images and photos of equipment. Paper edition (unseen), $145.95. Annotation copyrighted by Book News, Inc., Portland, OR
This book gives a progress report on the many and original contributions of radiation chemistry to the fundamental knowledge of the vast domain of chemical reactions and its applications. Radiation chemistry techniques indeed make it possible to elucidate detailed physicochemical mechanisms in inorganic and organic chemistry (including in space) and in biochemistry. Moreover, this comprehension is applied in materials science to precisely control syntheses by radiation, such as radiopolymerisation, radiografting, specific treatment of surfaces (textiles, paintings, inks, etc.), synthesis of complex nanomaterials, degradation of environmental pollutants and radioresistance of materials for nu...
Proton and Carbon Ion Therapy is an up-to-date guide to using proton and carbon ion therapy in modern cancer treatment. The book covers the physics and radiobiology basics of proton and ion beams, dosimetry methods and radiation measurements, and treatment delivery systems. It gives practical guidance on patient setup, target localization, and treatment planning for clinical proton and carbon ion therapy. The text also offers detailed reports on the treatment of pediatric cancers, lymphomas, and various other cancers. After an overview, the book focuses on the fundamental aspects of proton and carbon ion therapy equipment, including accelerators, gantries, and delivery systems. It then discu...