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Computational Drug Discovery
Computational methods and understanding computational models are important in modern drug discovery. The book focuses on computational approaches that can improve the development of in silico methodologies. It includes lead hit methods, docking algorithms, computational chiral compounds, structure-based drug design, GROMACS and NAMD, structural genomics, toxicity prediction, enzyme inhibitors and peptidomimetic therapeutics
Composing the Citizen
In a book that challenges modernist ideas about the value and role of music in Western society, Composing the Citizen demonstrates how music can help forge a nation. Deftly exploring the history of Third Republic France, Jann Pasler shows how French people from all classes and political persuasions looked to music to revitalize the country after the turbulent crises of 1871. Embraced not as a luxury but for its "public utility," music became an object of public policy as integral to modern life as power and water, a way to teach critical judgment and inspire national pride. It helped people to forget the past, voice conflicting aspirations, and imagine a shared future. Based on a dazzling su...
Antiviral Drugs
This book focuses on new small molecule approaches to combat viral infections. The chapters describe the discovery and development from bench through the clinic of relatively recently-approved antiviral drugs and compounds in advanced clinical development. Organized by a virus (such as HIV, HCV, RSV, influenza, HBV and CMV) and written by top academic and industrial authorities in the field, the book provides a unique opportunity to study, understand and apply discovery and development principles and learning without the need for an individual to research, analyze and synthesize all immense sourcing references. Topics showcase challenges and solutions of issues encountered, offering tremendous experience accumulated over many years of research that will be particularly useful to basic and bench scientists as well as clinicians as they continue discovering and developing new drugs and therapies.
Computational Approaches in Biotechnology and Bioinformatics
Volume 1 of Computational Approaches in Bioengineering—Computational Approaches in Biotechnology and Bioinformatics—explores many significant topics of biomedical engineering and bioinformatics in an easily understandable format. It explores recent developments and applications in bioinformatics, biomechanics, artificial intelligence (AI), signal processing, wearable sensors, biomaterials, cell biology, synthetic biology, biostatistics, prosthetics, big data, and algorithms. From applications of biomaterials in advanced drug delivery systems to the role of big data, AI, and machine learning in disease diagnosis and treatment, the book will help readers understand how these technologies a...
Drug Design and Action
This two volume book is an excellent introduction to this interdisciplinary area, lying on the interface between organic chemistry, biochemistry and medicine. The authors give a comprehensive overview of the field and outline the actual challenges in pharmaceutical science and industry. Volume 1 introduces the concepts of drug design and drug metabolic processes as well as antibacterial, antiviral and anticancer agents.
Drug Design and Action
A slow and consistent study of the approaches for drug design can help the foundation for a good scientific intuition. This edition includes over 30 new illustrations, numerous new mechanistic schemes and enhanced original figures. In addition, the use of color makes its study more pleasant and impressive. The Second Edition has been thoroughly revised with a modern look. The chapters on QSAR and Drug Metabolism have been extended, emphasizing concepts, such as the hyperconjugative effect or the anomeric effect, in which the student normally finds it difficult to understand. Stereoelectronic effects are essential to explain the mechanism of action of drugs and therefore, its agile and intuit...
Nutrition and Diet in Health
Nutrition and diet play a crucial role in sustaining good health throughout human lives. Food provides us with essential nutrients involved in many physiological activities and biological processes in the body including growth and development, metabolism, immune function, and overall well-being. Nutrition and Diet in Health: Principles and Applications reviews and discusses the issues related to the roles of nutrition and diet in human health and diseases. The book contains two sections – one section features principles, the other, covers applications. Part I provides information on sustainable use of nutrition and diets in health and diseases; advanced biotechnological approaches to impro...
Conquest of Invisible Enemies
In his latest book, science writer and medicinal chemist Jie Jack Li guides readers through the history of viruses, vaccines, and antiviral drugs. Li chronicles the discovery and treatment of HIV/AIDS, hepatitis, influenza, and coronaviruses. Throughout, Li focuses on how viruses have shaped human history and on the individuals who developed treatments.
Colonial Encounters in the Age of High Imperialism
Colonial Encounters in The Age of High Imperialism is the first book in the new HarperCollins World History Series, edited by Michael Adas. This title examines the world-transforming experience of Western imperialism during the period from 1870 to 1914. Case studies focusing Specifically on Belgium and the Congo, Hawaii and the United States, and India and Britain examine the experiences of both colonizers and colonized, men and women, elite officials and faceless laborers. An introductory overview makes the study of imperialism relevant for today's students by showing them how the past relates to the present. Chapter-ending conclusions summarize important material, and suggested in-depth readings direct students to sources for further exploration. The case studies provide detailed examination of particular places and moments and invite comparison with imperialism in other parts of the world. Discussions of broader topics and larger issues, such as population redistribution, the spread of technology, military invasion, and the role of guns and medicine build upon the case studies.
History in Dispute
Each volume of the History in Dispute series has a thematic, era or subject-specific focus that coincides with the way history is studied at the academic level. Each volume contains roughly 50 entries, chosen by a board of historians and academics.
