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The Inheritance
"The DeMoe family has the most devastating form of [Alzheimer's] that there is: early onset Alzheimer's, an inherited genetic mutation that causes the disease in 100 percent of cases, and has a 50 percent chance of being passed onto the next generation. Of the six DeMoe children whose father had it, five have inherited the gene; the sixth, Karla, has inherited responsibility for all of them. But rather than give up in the face of such news, the DeMoes have agreed to spend their precious, abbreviated years as part of a worldwide study that could utterly change the landscape of Alzheimer's research and offers the brightest hope for future treatments--and possibly a cure"--
Clinical Geriatric Psychopharmacology
Thoroughly updated for its Fourth Edition, this volume is the most authoritative clinical reference on the pharmacologic treatment of psychiatric disorders in elderly patients. This edition provides complete information on new psychotropic drugs, new uses for established drugs, and clinically relevant advances in the neurosciences. Four new chapters cover genes, pharmacokinetics, and their impact on prescribing; new cognitive-enhancing strategies and drugs; late-life depression and physical illness; and depression and cardiac disease in late life. The book offers detailed guidelines—including drug names, dosages, and prescribing recommendations—for pharmacologic treatment of specific disorders. Chapters include clinical vignettes and tables presenting current clinical trial data. Appendices provide succinct information on prescribing and drug interactions.
Alzheimer’s Disease: Advances for a New Century
This volume is a companion to the highly successful book published in association with the Journal of Alzheimer’s Disease (JAD) on the centennial of Alzheimer’s discovery: “Alzheimer’s Disease: A Century of Scientific and Clinical Research”. Instead of looking back, this collection, “Alzheimer’s Disease: Advances for a New Century”, will look forward. Using scientometric analysis the most promising developments since the Alzheimer Centennial in 2006 have been substantiated. While prior trends and advances in genetics, amyloid-?, tau, neuropathology, and oxidative stress continue as active areas, emergent areas impacting the transition from normal cognition to Alzheimer’s disease such as diagnostic imaging, biomarkers, metabolism, and lifestyle (areas conceived only a few years ago) now dominate the debate. Invited contributors have summarized their landmark publications identified by our analysis and have put them into perspective, explaining the impetus behind the work, the contribution of the results to the field, and who played a role in the work.
The Familiar Stranger Who Lives In Our Home
Nancy Reagan. David Hyde Pierce. Princess Yasmin. We share something with all three. That's why you have this book in your hand. Each has had a loved one ravaged by Alzheimer's Disease. We watched them morph into complete strangers who continue to look the same. Famous or not, the five million Alzheimer's victims in this country and their families are people trying to get through this tragedy. Whether beginning the search for diagnosis, adjusting to its reality, or wondering if you are doing the right thing, you are eager for answers. Whether the victim is in the early, moderate or severe stage you have doubts. Been there and done that. To the astonishment of doctors, we kept my wife at home and thriving for thirteen years with moderate to severe Alzheimer's Disease. To do that takes dedication, planning and faith. However, we are ordinary people and we did it. Many of you can too. I wrote this book because this disease has touched nearly a hundred friends either as victims, relatives or caregivers. During one half hour at my fifty-fifth college reunion, I learned of three more stricken classmates. This book is for them, their friends, families, and you.
The Alzheimer Conundrum
Why our approaches to Alzheimer's and dementia are problematic and contradictory Due to rapidly aging populations, the number of people worldwide experiencing dementia is increasing, and the projections are grim. Despite billions of dollars invested in medical research, no effective treatment has been discovered for Alzheimer's disease, the most common form of dementia. The Alzheimer Conundrum exposes the predicaments embedded in current efforts to slow down or halt Alzheimer’s disease through early detection of pre-symptomatic biological changes in healthy individuals. Based on a meticulous account of the history of Alzheimer’s disease and extensive in-depth interviews, Margaret Lock highlights the limitations and the dissent associated with biomarker detection. Lock argues that basic research must continue, but should be complemented by a public health approach to prevention that is economically feasible, more humane, and much more effective globally than one exclusively focused on an increasingly harried search for a cure.
Alzheimer's Disease
Alzheimer's Disease is an ever present problem affecting millions of people around the world and, as people's average lifespan lengthens, its prevalence is set to increase. A global effort is needed to combat the disease, including research to investigate the causes, development of effective treatments and, ultimately, prevention of the disease. Published every two years, these timely books discuss the very latest research. This new volume provides a unique source of reference to the important work being done in this field, it gives academics and clinicians an opportunity to learn about cutting edge developments and covers all aspects of Alzheimer's Disease, including diagnosis, clinical course, epidemiological course and therapeutics and disease mechanisms. Alzheimer's Disease: Advances in Etiology, Pathogenesis and Therapeutics will provide essential information for basic and clinical researchers in Alzheimer's Disease and other dementias as well as for those who care for patients.
Ministry with Persons with Mental Illness and Their Families, Second Edition
Those who are afflicted as well as those who are adversely affected by mental illness often live lives of "quiet desperation" without recourse to appropriate assistance. Most caregivers confronted with these illnesses in the work of ministry have had no training or accurate information about mental illnesses, so frequently they do nothing, resulting in further harm and damage. Others may operate out of a theological system that does not adequately account for the nature, severity, or treatment of these illnesses. In Ministry with Persons with Mental Illness and Their Families, Second Edition, psychiatrists and pastoral theologians come together in an interdisciplinary, collaborative effort to ensure accuracy of information concerning the medical dimensions of mental illness, interpret these illnesses from a faith perspective, and make suggestions relative to effective ministry. Readers will learn how science and a faith tradition can not only co-exist but work in tandem to alleviate the pain of the afflicted and affected.
Alzheimer: 100 Years and Beyond
Few medical or scientific addresses have so unmistakeably made history as the presentation delivered by Alois Alzheimer on November 4, 1906 in Tübingen. The celebratory event "Alzheimer 100 Years and Beyond" was organized through the Alzheimer community in Germany and worldwide, in collaboration with the Fondation Ipsen. This volume, a collection of articles by the invited speakers and of a few other prominent researchers, is published as a record of those events.
