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The tumor microenvironment (TME) plays a critical role in tumor proliferation, progression, and therapeutic responses. TME is a complex network of cancer cells, stromal cells, and, most importantly, infiltrating immune cells. Cancer cells regulate numerous biological functions through direct or indirect interaction with TME components. Emerging evidence suggests that TME crucially influences the response to both chemotherapy and immunotherapy. As scientific research has entered the big data era with the fast development of high-throughput sequencing technologies, machine learning has been gradually widely applied to extract important knowledge from big data bioinformatics. Thus, characterizing the TME landscape in cancer and identifying different immune-related TME phenotypes using machine learning-based bioinformatics analyses, in vitro experiments, and in vivo experiments are of great interest and significance.
The Rice Genetics Collection of past symposia and other selected literature contains nearly 4,400 pages of searchable information on rice genetics and cytogenetics published by the IRRI and its partners since 1964. In addition to the five genetics symposia held at 5-year intervals since 1985, the collection contains classic publications that kicked off significant reporting on these subjects in the early 1960s. This collection is a comprehensive and historical documentation on the subject of rice genetics, spanning 45 years of research and scholarly work.Published in 2003, Advances in Rice Genetics is a supplement to Rice Genetics IV. It contains 241 short chapters from various contributors on topics dealing with the genetics and breeding of agronomic traits; genetic diversity, evolution, and alien introgression; molecular markers, QTL mapping, and marker-assisted selection; genomics; gene isolation and function; tissue culture and transformation; and genetics of rice pathogens.
This book presents recent results on nonlinear parabolic-hyperbolic coupled systems such as the compressible Navier-Stokes equations, and liquid crystal system. It summarizes recently published research by the authors and their collaborators, but also includes new and unpublished material. All models under consideration are built on compressible equations and liquid crystal systems. This type of partial differential equations arises not only in many fields of mathematics, but also in other branches of science such as physics, fluid dynamics and material science.
By examining all the prevalent varieties of therapy from self-care to religious ritual, this book explores health care practices in China, before modern times. In ancient China most people were unable to afford a doctor, even in the unlikely case that one lived near their village and was willing to treat peasants. What did they do when their children got sick? The answer is to be found in this book, which goes far beyond the history of medicine. The author uses methods of medical anthropology to explain the curative roles of popular religion, Daoism, Buddhism and the therapeutic rites performed by imperial officials. Readers will discover the steady interaction of religious healing and classical medicine in this culture. This highly readable book builds on over forty years of study and analysis of early liturgical and medical writings and a wide variety of other sources. Its focus on the eleventh century throws new light on a period of rapid transition in many aspects of therapy and it will appeal to scholars and general readers alike.
This is the first book to focus on respiratory health and diseases in Asia, where 60% of the world’s population reside. It is well known that disease patterns and health care delivery vary in different parts of the world. With divergent socioeconomic background, genetic makeup and environmental factors, health care issues take on a unique perspective in Asia. In this volume, respiratory health and diseases are presented and discussed with relevance to their unique epidemiology and management in Asia. The chapters are contributed by professional leaders who are highly respected for their clinical expertise in respiratory medicine in different parts of Asia. Many of them are internationally ...
Zi Zhi Tong Jian (Chinese: 资治通鉴;English: "Comprehensive Mirror in Aid of Governance") is a pioneering reference work in Chinese historiography, published in 1084 in the form of a chronicle. In 1065 AD, Emperor Yingzong of Songordered the great historian Sima Guang (1019–1086 AD) to lead with other scholars such as his chief assistants Liu Shu, Liu Ban and Fan Zuyu, the compilation of a universal history of China. The task took 19 years to be completed,and, in 1084 AD, it was presented to his successor Emperor Shenzong of Song. The Zi Zhi Tong Jian records Chinese history from 403 BC to 959 AD, covering 16 dynasties and spanning across almost 1,400 years,and contains 294 volumes (...
The COVID-19 pandemic is unlike anything the world has ever seen before. Its reach is wide, and its effects have been debilitating. Understanding this particular strain of the coronavirus and knowing the best ways to recover are more important than ever. Rehabilitation from COVID-19: An Integrated Traditional Chinese and Western Medicine Protocol contains basic knowledge about COVID-19, including its etiology, pathogenesis, and treatment both in traditional Chinese medicine and Western medicine. It also includes relative assessment and rehabilitation targeting residual dysfunctions due to COVID-19, such as pulmonary dysfunction, mental disorders, and malnutrition, among others. Key Features ...