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With more restrictions upon animal experimentations, pharmaceutical industries are currently focusing on a new generation of experiments and technologies that are considerably more efficient and less controversial. The integration of computational and experimental strategies has led to the identification and development of promising compounds. Computer Applications in Drug Discovery and Development is a pivotal reference source that provides innovative research on the application of computers for discovering and designing new drugs in modern molecular biology and medicinal chemistry. While highlighting topics such as chemical structure databases and dataset utilization, this publication delves into the current panorama of drug discovery, where high drug failure rates are a major concern and properly designed virtual screening strategies can be a time-saving, cost-effective, and productive alternative. This book is ideally designed for chemical engineers, pharmacists, molecular biologists, students, researchers, and academicians seeking current research on the unexplored avenues and future perspectives of drug design.
In today's fast-paced and modern world, our lifestyles have undergone a dramatic shift. The conveniences and comforts that accompany our technological advancements have come at a cost – an increased prevalence of lifestyle diseases. Lack of physical activity, stress, sedentary habits, and poor dietary choices have become leading causes of a spurt in varied health complications such as obesity, diabetes, and cardiovascular diseases. Various health awareness programmes organized by central/state governments, private organizations, and NGOs from time to time have generated interest among common people in exploring organic foods that are free from chemicals and full of nutraceuticals. There ha...
This book offers insights into the recent research focusing on green solutions to address environmental pollution and its impacts. Bioremediation is a vast area that encompasses numerous innovative and cost-effective experimental and research methods involvingnumerous technologies, such as biotechnological, biochemical, microbial, marine, chemical and engineering approaches. Featuring original research and review articles by leading experts, the book explores potential solutions to the growing issues of waste management and environmental pollution and their impacts, and suggests future research directions. As such, it is a valuable resource for professionals and general readers alike.
Nanoparticles have a smaller size as compared to their micro, macro, or bulk counterparts. Reduction in size of these particles provides them with some unique characteristics, such as surface-to-volume ratio, quantum confinement effect, surface plasmon response, widening of band gap, etc. These nanoparticles have attracted attention of scientists all over the globe in last few decades. Written in a convenient and easy-to-read style, this book covers the important aspects of nanomaterials by focusing on the many issues related to the food and textile industries, treatment of polluted water, health, energy crises, targeted drug delivery, etc. The editors take an interdisciplinary approach to discussing how the scenario will change on a global level in the future and explore when these nanomaterials will replace almost all micro- and macromaterials. The Science of Nanomaterials is a ready-at-hand guide to the many issues related to the use of nanomaterials in drug and gene delivery, sensors, photosplitting of water, wastewater treatment, microbial diagnosis, textile industries, nanocomposites, food industries (safety, security, packaging and preservation), etc.
The current book emphasizes on basic knowledge of chemistry and biology concepts, covering multidisciplinary applications which comprises functional aspects of chemical and biological disciplines and they are resource material for young innovative minds to enhance their knowledge and research thoughts as a creative element to apply it in their research in the field of chemical biology. The main motto of this book highlights on research objectives, new developments of synthesis, a wide range of applications, and as per the industrial requirements for a useful product to launch or discover for science and society. Various innovations are the major source and new perspectives to troubleshoot th...
Biological engineering is a field of engineering in which the emphasis is on life and life-sustaining systems. Biological engineering is an emerging discipline that encompasses engineering theory and practice connected to and derived from the science of biology. The most important trend in biological engineering is the dynamic range of scales at which biotechnology is now able to integrate with biological processes. An explosion in micro/nanoscale technology is allowing the manufacture of nanoparticles for drug delivery into cells, miniaturized implantable microsensors for medical diagnostics, and micro-engineered robots for on-board tissue repairs. This book aims to provide an updated overview of the recent developments in biological engineering from diverse aspects and various applications in clinical and experimental research.
This book comprehensively reviews the recent developments of natural polymers for drug delivery systems in various lung disorders. The initial chapter provides a brief introduction to lung diseases with a focus on the current landscape of natural polymers and trends in understanding the disease pathology. Several chapters of the book devoted to the latest technologies and advances in drug delivery systems include practical solutions on designing more effective drug delivery systems based on natural polymers that can be used in the management of lung diseases. Further, the book presents biodegradable and bio-reducible- natural polymers- based drug delivery systems for lung diseases. Towards the end, the book examines future prospects and challenges of natural polymers-based drug delivery systems in combating lung diseases. This book is useful for phytochemists, formulation/drug delivery, biological and translational researchers and clinicians working in the field of lung disorders.
The goal of any novel drug delivery system is to provide therapeutic benefits to the patients by increasing duration of drug action, reducing dosing frequency, and controlling drug release rate at the target site, thereby reducing unwanted side effects. Advanced Technology for Delivering Therapeutics is a reference book that covers recent developments in the field of drug delivery science and technology. The purpose of this book is to bring together descriptions of some selective technologies including new and promising nanotechnology currently being investigated for drug delivery applications. This book is a useful source of information for graduate and post-graduate students of pharmacy and biomedical science; pharmaceutical
This book focuses on natural products, in particular medicinal plants and their derived products, as an indispensable source of bioactive molecules that serve as either drug candidates or lead compounds for drug design and discovery . There are several advantages for plant-derived therapeutics, including wide availability, diverse pharmacological actions, and a generally good profile of safety and tolerability. Over the recent years, there have been numerous reports from clinical studies testifying the efficacy and safety of medicinal plants and phytochemicals in treating human diseases. A plethora of basic studies has also unraveled molecular mechanisms underlying the health benefits of her...
Resumen: Surface contamination is of cardinal importance in a host of technologies and industries, ranging from microelectronics to optics to automotive to biomedical. Thus, the need to understand the causes of surface contamination and their removal is very patent. Generally speaking, there are two broad categories of surface contaminants: film-type and particulates. In the world of shrinking dimensions, such as the ever-decreasing size of microelectronic devices, there is an intensified need to understand the behavior of nanoscale particles and to devise ways to remove them to an acceptable level. Particles which were functionally innocuous a few years ago are ̥killer defects̲ today, wit...