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PI3K-mTOR in Cancer and Cancer Therapy
In the post human-genome project era, cancer specific genomic maps are redesigning tumor taxonomy by evolving from histopathology to molecular pathology. The success of a cancer drug today is fundamentally based on the success in identifying target genes that control beneficial pathways. The overwhelming power of genomics and proteomics has enlightened researchers about the fact that the PI3K-mTOR pathway is the most commonly up-regulated signal transduction pathway in various cancers, either by virtue of its activation downstream of many cell surface growth factor receptors or by virtue of its collateral and compensatory circuitry with RAS-MAPK pathway. Oncogenic signaling in the majority o...
AACR 2017 Proceedings: Abstracts 1-3062
The AACR Annual Meeting highlights the best cancer science and medicine from institutions all over the world. Attendees are invited to stretch their boundaries, form collaborations, attend sessions outside their own areas of expertise, and learn how to apply exciting new concepts, tools, and techniques to their own research. Part A contains abstracts 1-3062 accepted for the 2017 meeting.
A House of Rain and Snow
It's so real. It must have happened. Or it's happening. Or, it's bound to happen. I trust Srijato's every word in this novel-Gulzar Pushkar, an offspring of the most incredible of times, has next to nothing to call his own. Except for a seasoned but out-of-work and disheartened father, and a defiant, uncompromising mother with a truly astounding gift for music. It is only in the gradually widening chasm between his parents that he discovers his world of poems, which he desperately tries to hide from everyone. Everyone else except Saheli that is, only she gets to read his poems. Saheli, his schoolfriend who he is in love with. Abhijit, another friend from school, is unwilling to leave it all ...
Fundamentals of Investments
This introduction provides a clear framework for understanding and analyzing securities, and covers the major institutional features and theories of investing. While the book presents a thorough discussion of investments, the authors keep the material practical, relevant, and easy to understand. The latest developments in investments are brought to life through the use of tables, graphs, and illustrations that incorporate current market information and academic research. An international content deals directly with international securities and securities markets throughout the book--along with currency management and interest rate parity. Up-to-date "Money Matters" articles reflect the latest real-world developments and are provided throughout each chapter to give readers a sense of how practitioners deal with various investment issues and use techniques. Other coverage includes an array of investment tools--presented through discussions on stocks, bonds, and other securities such as options and futures. A guide to reviewing, forecasting, and monitoring--for individuals preparing to make investments or take the CFA exam.
Yesterday’s Melodies Today’s Memories
Yesterday’s Melodies Todays Memories is a rare collection of profiles of all important music-makers of the Hindi Film Industry between 1931 and 1970. It not only gives a biographical background of each music artiste, but it goes further to interview many of the surviving giants and completes the task by listing some of the best songs with which that person is associated. Here are singers that include the whole gamut from KL Saigal to Asha Bhosle, lyricists that include Sahir and Gulzar, music composers from Naushad to RD Burman, artistes that were part-time singers and full time actors like Ashok Kumar, melody queens like Noor Jahan and Lata Mangeshkar, gentlemen lyricists like Prem Dhawan...
Algorithms and Protocols for Wireless Sensor Networks
Boukerche is well-known and established international researcher in the field of wireless mobile networks and distributed systems. This is one of the first publications to focus on wireless ad hoc and sensor networks with a concentration on algorithms and protocols providing you with a comprehensive resource to learn about the continuous advances in wireless and mobile communications.
The Routledge Companion to Iberian Studies
This book provides a comprehensive, state-of-the-art account of the field, reaffirming Iberian Studies as a dynamic and evolving discipline offering promising areas of future research. It is an essential tool for research in Iberian Studies.
Interrogating the Theory and Practice of Communication for Social Change
A new addition to the Palgrave Studies in Communication for Social Change series, this book sets the stage for subsequent books by identifying and analysing the current gaps in the field. It critically reviews the theory, practice and strategies of Communication for Social Change in relation to occurring structures, policies and discourses.
