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The world of targeted drug delivery (TDD) represents an incredible leap forward in how we treat and manage diseases . It’s a frontier where science converges with hope, precision, and, in many ways, a reimagining of healthcare itself. As we move closer to realizing a future where therapies can target specific cells or tis-sues with minimal side effects, the excitement is tempered by a growing recogni-tion of the technical, ethical, and societal challenges that come with this revolu-tionary shift in medical practice. In this drawing from the insights of re-searchers and thinkers who are deeply engaged in navigating this transformative field. Together, the following chapters, illustrate how the evolving landscape of TDD holds both immense promise and significant complexity.
Toxicological Risk Assessment and Multisystem Health Impacts From Exposure highlights the emerging problems of human and environmental health attributable to cumulative and multiple sources of long-term exposure to environmental toxicants. The book describes the cellular, biological, immunological, endocrinologic, genetic, and epigenetic effects of long-term exposure. It examines how the combined exposure to nanomaterials, metals, pharmaceuticals, multifrequency radiation, dietary mycotoxins, and pesticides accelerates ecotoxicity in humans, animals, plants, and the larger environment. The book goes on to also offer insights into mixture risk assessments, protocols for evaluating the risks, ...
Exposure and Risk Assessment of Pesticide Use in Agriculture: Approaches, Tools and Advances offers an overview of the different methods available in toxicology for pesticide exposure and risk assessment, ranging from the regulatory field, to in-field research studies. The book provides technical background on each method, describing known and grounded tools, new uses of tools and development prospects. This book is ideal for researchers in pesticide toxicology, exposure toxicology, toxicologic risk assessment, occupational hygiene and medicine, and pesticide toxicology as well as occupational health and industrial hygiene practitioners, regulatory experts of corporate and public bodies, and advanced students.
This book highlights the medical importance of and increasing global interest in herbal medicines, herbal health products, herbal pharmaceuticals, nutraceuticals, food supplements, herbal cosmetics, etc. It also addresses various issues that are hampering the advancement of Indian herbal medicine around the globe; these include quality concerns and quality control, pharmacovigilance, scientific investigation and validation, IPR and biopiracy, and the challenge that various indigenous systems of medicine are at risk of being lost. The book also explores the role of traditional medicine in providing new functional leads and modern approaches that can offer elegant strategies for facilitating t...
Information Resources in Toxicology, Third Edition is a sourcebook for anyone who needs to know where to find toxicology information. It provides an up-to-date selective guide to a large variety of sources--books, journals, organizations, audiovisuals, internet and electronic sources, and more. For the Third Edition, the editors have selected, organized, and updated the most relevant information available. New information on grants and other funding opportunities, physical hazards, patent literature, and technical reports have also been added.This comprehensive, time-saving tool is ideal for toxicologists, pharmacologists, drug companies, testing labs, libraries, poison control centers, phys...
GMOS and Political Stance: Global GMO Regulation, Certification, Labeling, and Consumer Preferences provides a foundational-to-current challenges resource for those involved in developing and applying regulations to these important resources. Beginning with basics of GMOs, the book first familiarizes the reader with the history, economic status, associated risks, global politics, and socio-economics of GMOs. From exploring the necessity of GMO regulations with the existing GMO technology as well as new gene editing technologies to discussion by GMO regulations experts from different continents and countries, readers will find the information necessary to understand the laws, rules, regulatio...
Due to the resultant health consequences and considerable increase in prevalence, obesity has become a major worldwide health problem. “Obesity and Lipotoxicity” is a comprehensive review of the recent researches to provide a better understanding of the lipotoxicity-related mechanisms of obesity and the potential for the development of new treatment strategies. This book overviews the biochemical pathways leading to obesity-related metabolic disorders that occur subsequent to lipotoxicity. Chapters examine the deleterious effects of nutrient excess at molecular level including the cellular and molecular aspects of breast cancer, resistance to leptin, insulin, adiponectin, and interconnection between the circadian clock and metabolic pathways during high-fat feeding. “Lipotoxicity and Obesity” will be a useful resource for clinicians and basic science researchers, such as biochemists, toxicologists, immunologists, nutritionists, adult and pediatric endocrinologists, cardiologists, as well as students who are thought in this field.
Nas atuais sociedades plurais (e multiculturais), a introdução intencional de OGM’s no ambiente – em particular o seu cultivo e comercialização – gera problemas jurídicos poliédricos, os quais atravessam o direito privado e o direito público. Avultam questões decorrentes dos complexos procedimentos administrativos nacionais com efeitos transnacionais, passando pelos procedimentos administrativos nacionais associados a sistemas de reconhecimento mútuo de cultivo e introdução no comércio destes OGM’s; qual “europeização” destes procedimentos versus a sua “renacionalização”. São também importantes os problemas decorrentes da responsabilidade civil (dos particul...
This book provides a comprehensive overview of aging and its mechanisms through the prism of telomere length and its link to lifestyle parameters and environmental pollutants, diseases where telomere length attrition is prominent, and therapeutic approaches to slow down or prevent the process of telomere length reduction. It also provides an extensive comparison of the methodology for telomere length determination and characterization. The book will help researchers in any discipline to obtain an in-depth and broad knowledge of the most recent advances in telomere research written by specialists in the field. It is also addressed to the readers interested in gaining an insight into the processes of aging and those factors that affect “graceful” aging, enabling them to extract even useful tips in improving their everyday habits.