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Rethinking Cancer
Leading scientists argue for a new paradigm for cancer research, proposing a complex systems view of cancer supported by empirical evidence. Current consensus in cancer research explains cancer as a disease caused by specific mutations in certain genes. After dramatic advances in genome sequencing, never before have we known so much about the individual cancer cell--and yet never before has it been so unclear what to do with this knowledge. In this volume, leading researchers argue for a new theory framework for understanding and treating cancer. The contributors propose a complex systems view of cancer, presenting conceptual building blocks for a new research paradigm supported by empirical...
Weak Links
How can our societies be stabilized in a crisis? Why can we enjoy and understand Shakespeare? Why are fruitflies uniform? How do omnivorous eating habits aid our survival? What makes the Mona Lisa’s smile beautiful? How do women keep our social structures intact? – Could there possibly be a single answer to all these questions? This book shows that the statement: "weak links stabilize complex systems" provides the key to understanding each of these intriguing puzzles, and many more besides. The author, a recipient of several distinguished science communication prizes, explains weak or low probability interactions, and uses them as connecting threads in a vast variety of networks from proteins to ecosystems. This unique book and the ideas it develops will have a significant impact on diverse, seemingly unrelated fields of study.
Implementing Ecological Integrity
This book contains some of the papers which were presented at the NATO Science, Environmental Security, Advanced Research Workshop on "Implementing Ecological Integrity: Restoring Regional and Global Environmental and Human Health" held in Budapest from June 26 to July 1, 1999. All papers presented are summarized in the Introduction and, in some cases, shorter versions are published. A mUltidisciplinary core of American and Western European participants had met over the preceeding years to discuss the concept of ecological integrity. The term "ecological integrity" is found in environmental policy documents but, generally, is not defined. It competes with other recent terms, or environmental...
Fresh Voices from the Periphery
Fresh Voices from the Periphery is evidence that history matters — not only the study of the past — but also by shedding light on how events of the past have impacted lives in the present. You are holding in your hands a collection of thought-provoking essays written by young people whose families have lived as minorities in various countries in east-central Europe for four generations. They became minorities not because their families migrated to different parts of Europe, but because the borders were changed overnight by the Treaty of Trianon after the end of the First World War. Much has been written about the outcomes of Trianon, but this book is very different. These essays are the ...
Complex Networks and their Applications
Fuelled by the big data paradigm, the study of networks is an interdisciplinary field that is growing at the interface of many branches of science including mathematics, physics, computer science, biology, economics and the social sciences. This book, written by experts from the Network Science community, covers a wide range of theoretical and practical advances in this highly active field, highlighting the strong interconnections between works in different disciplines. The eleven chapters take the reader through the essential concepts for the structural analysis of networks, and their applications to real-world scenarios. Being self-contained, the book is intended for researchers, graduate and advanced undergraduate students from different intellectual backgrounds. Each chapter combines mathematical rigour with rich references to the literature, while remaining accessible to a wide range of readers who wish to understand some of the key issues encountered in many aspects of networked everyday life.
Rebellion
. . tiny differences in the nature of individuals require that each of usdiscovers, arranges, and sustains his or her unique partnerships andterritories. Because of this uniqueness you must actively steer your life rather that just letting it happen. None of us is mere clay for environment's thumbs and even the youngest of ten children is a one-off architect who renovates his parents. Using clarity, humor, and personal examples, Dr. James Brody shows why you simplify or complicate your life, form partnerships and social networks, and sometimes conform or not. He also explains why certain aspects of physics are your best friends, why your commonsense handles them so well, why women displace m...
Gifted Education as a Lifelong Challenge
This book is dedicated to the scholar and academic teacher Franz Monks, who is considered internationally to be one of the most brilliant 'giftedness' researchers. The wide spectrum of his writings and activities is reflected in the number of renowned international scholars who contributed to this unique collection of essays on gifted education as a life-long challenge.
New Challenges for Cancer Systems Biomedicine
The future of oncology seems to lie in Molecular Medicine (MM). MM is a new science based on three pillars. Two of them are evident in its very name and are well known: medical science and molecular biology. However, there is a general unawareness that MM is firmly based on a third, and equally important, pillar: Systems Biomedicine. Currently, this term denotes multilevel, hierarchical models integrating key factors at the molecular, cellular, tissue, through phenotype levels, analyzed to reveal the global behavior of the biological process under consideration. It becomes increasingly evident that the tools to construct such complex models include, not only bioinformatics and modern applied statistics, as is unanimously agreed, but also other interdisciplinary fields of science, notably, Mathematical Oncology, Systems Biology and Theoretical Biophysics.
Information Technology and Open Source: Applications for Education, Innovation, and Sustainability
This book constitutes revised selected papers from the following SEFM 2012 satellite events: InSuEdu, the First International Symposium on Innovation and Sustainability in Education; MokMaSD, the First International Symposium on Modelling and Knowledge Management for Sustainable Development and Open Cert, the 6th International Workshop on Foundations and Techniques for Open Source Software Certification, held in Thessaloniki, Greece, in October 2012. The total of 14 regular papers and 7 short papers included in this volume were carefully reviewed and selected from 35 submissions. The papers cover the topics related to the use of Information and Communication Technology (ICT) and Open Source Software (OSS) as tools to foster and support Education, Innovation and Sustainability.
