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This volume provides an interdisciplinary analysis of current biological applications of poly(ethylene glycol) (PEG). It includes a wide array of topics useful to materials scientists, organic chemists, biochemists, and bioengineers interested in drug delivery systems, pharmaceuticals and other biomaterials. The applications discussed include PEG-modified proteins, liposomes, drugs, surfaces of materials, and hydrogels. The volume also includes a review of PEG-oligonucleotides and a concise summary of the toxicology of PEG and its derivatives.
Dmitri Shostakovich (1906-75) was one of the greatest composers of the 20th century, as well as the first major Soviet composer. In the fourth edition of Dmitri Shostakovich Catalogue: The First Hundred Years and Beyond, Derek C. Hulme names and describes all known musical compositions of the Russian composer. More than 175 major works are annotated and discussed, including such comprehensive details as titles and subtitles, dates of composition, instrumentation, and duration; information on dedications and premieres; arrangements by the composer and others; publication details; notes on bibliographical references and the location of the autograph score; and comprehensive chronological lists...
Marieke de Mooij answers the fundamental questions about consumption in this new edition, using her own model of consumer behavior that integrates culture in the self, in personality and in people’s relationships with others.
The finite-state paradigm of computer science has provided a basis for natural-language applications that are efficient, elegant, and robust. This volume is a practical guide to finite-state theory and the affiliated programming languages lexc and xfst. Readers will learn how to write tokenizers, spelling checkers, and especially morphological analyzer/generators for words in English, French, Finnish, Hungarian, and other languages. Included are graded introductions, examples, and exercises suitable for individual study as well as formal courses. These take advantage of widely-tested lexc and xfst applications that are just becoming available for noncommercial use via the Internet.
Presents the main developments of the past 20 years, relating advances in systems that release the active drug in a sustained and controlled way, and new drugs that address more specifically the tissues and cells with which they are designed to interact. Considers the problems of biodistribution and biodegradation, with in-depth discussion of the selectivity and toxicity of the drugs administered by the various carrier systems. Topics covered range from antibodies, polymers, liposomes, erythrocytes and erythrocyte ghosts, to implantable infusion pumps. Acidic paper. Annotation copyrighted by Book News, Inc., Portland, OR
Currently, used anticancer drugs are found to be poorly water soluble and highly potent in nature. They act non-selectively on both tumour as well as normal cells. This non-selectivity is being tried to overcome by means of selective or targeted tumor drug delivery with improvised safety and efficacy. This book discusses nanocarrier systems for drug delivery.
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What's new in dendrimer research? Just as these fascinating giant molecules are continuing to ramify, new perspectives and challenges continue to emerge. This bestseller on dendritic molecules discusses the latest developments in the synthesis and application of these macromolecules. It gives a comprehensive, up-to-date account of the topic, from the historical overview and theoretical background up to the most recent achievements. Having shaped this scientific field, the authors are able to brilliantly combine the basic principles with a wealth of more advanced information. The optimal presentation of the structural features of dendrimers helps readers to quickly understand even sophisticated syntheses. For special synthetic problems, the well-selected, detailed list of references allows easy access to further literature. This monograph will undoubtedly prove to be of interest for both beginners and advanced scientists in organic and pharmaceutical chemistry, as well as material science.