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Handbook of Sepsis
This practically oriented book provides an up-to-date overview of all significant aspects of the pathogenesis of sepsis and its management, including within the intensive care unit. Readers will find information on the involvement of the coagulation and endocrine systems during sepsis and on the use of biomarkers to diagnose sepsis and allow early intervention. International clinical practice guidelines for the management of sepsis are presented, and individual chapters focus on aspects such as fluid resuscitation, vasopressor therapy, response to multiorgan failure, antimicrobial therapy, and adjunctive immunotherapy. The closing section looks forward to the coming decade, discussing novel trial designs, sepsis in low- and middle-income countries, and emerging management approaches. The book is internatio nal in scope, with contributions from leading experts worldwide. It will be of value to residents and professionals/practitioners in the fields of infectious diseases and internal medicine, as well as to GPs and medical students.
Contemporary Issues in Estuarine Physics
Estuaries are of high socioeconomic importance with twenty-two of the thirty-two largest cities in the world located on river estuaries. Estuaries bring together fluxes of fresh and saline water, as well as fluvial and marine sediments, and contain high biological diversity. Increasingly sophisticated field observation technology and numerical modeling have produced significant advances in our understanding of the physical properties of estuaries over the last decade. This book introduces a classification for estuaries before presenting the basic physics and hydrodynamics of estuarine circulation and the various factors that modify it in time and space. It then covers special topics at the forefront of research such as turbulence, fronts in estuaries and continental shelves, low inflow estuaries, and implications of estuarine transport for water quality. Written by leading authorities on estuarine and lagoon hydrodynamics, this volume provides a concise foundation for academic researchers, advanced students and coastal resource managers.
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