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Drug Discovery
Sets forth the history, state of the science, and future directions of drug discovery Edited by Jie Jack Li and Nobel laureate E. J. Corey, two leading pioneers in drug discovery and medicinal chemistry, this book synthesizes great moments in history, the current state of the science, and future directions of drug discovery into one expertly written and organized work. Exploring all major therapeutic areas, the book introduces readers to all facets and phases of drug discovery, including target selection, biological testing, drug metabolism, and computer-assisted drug design. Drug Discovery features chapters written by an international team of pharmaceutical and medicinal chemists. Contribut...
Symmetries in Science III
Nicely printed and bound proceedings of a major symposium contain 29 reviews of highly diverse developments in the world of symmetry, plus 14 rather briefer research papers. The variety of the topics treated and the authority of the contributors suggest that most physical theorists will find here so
Differential Geometric Methods in Mathematical Physics
The focal topic of the 14th International Conference on Differential Geometric Methods was that of mathematical problems in classical field theory and the emphasis of the resulting proceedings volume is on superfield theory and related topics, and classical and quantized fields.
Topological Properties and Global Structure of Space-Time
The Ninth Course of the International School of Cosmology and Gravita tion of the Ettore Majorana Centre for Scientific Culture is concerned with "Topological Properties and Global Structure of Space-Time." We consider this topic to possess great importance. Our choice has also been influenced by the fact that there are many quest ions as yet unre solved. Standard general relativity describes space-time as a four-dimensional pseudo-Riemannian manifold, but it does not prescribe its large-scale structure. Inorderto attempt answers to some topological questions, such as whether our universe is open or closed, whether it is orientable, and whether it is complete or possesses singularities, vari...
Special Matrices of Mathematical Physics
Ch. 1. Some fundamental notions. 1.1. Definitions. 1.2. Components of a matrix. 1.3. Matrix functions. 1.4. Normal matrices -- ch. 2. Evolving systems -- ch. 3. Markov chains. 3.1. Non-negative matrices. 3.2. General properties -- ch. 4. Glass transition -- ch. 5. The Kerner model. 5.1. A simple example: Se-As glass -- ch. 6. Formal developments. 6.1. Spectral aspects. 6.2. Reducibility and regularity. 6.3. Projectors and asymptotics. 6.4. Continuum time -- ch. 7. Equilibrium, dissipation and ergodicity. 7.1. Recurrence, transience and periodicity. 7.2. Detailed balancing and reversibility. 7.3. Ergodicity -- ch. 8. Prelude -- ch. 9. Definition and main properties. 9.1. Bases. 9.2. Double Fo...
Geometric And Algebraic Topological Methods In Quantum Mechanics
In the last decade, the development of new ideas in quantum theory, including geometric and deformation quantization, the non-Abelian Berry's geometric factor, super- and BRST symmetries, non-commutativity, has called into play the geometric techniques based on the deep interplay between algebra, differential geometry and topology. The book aims at being a guide to advanced differential geometric and topological methods in quantum mechanics. Their main peculiarity lies in the fact that geometry in quantum theory speaks mainly the algebraic language of rings, modules, sheaves and categories. Geometry is by no means the primary scope of the book, but it underlies many ideas in modern quantum physics and provides the most advanced schemes of quantization.
Theory of P-adic Distributions
A wide-ranging 2010 survey of new and important topics in p-adic analysis for researchers and graduate students.
