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Remembrance of Things Past It scarcely seems credible that it was almost exactly thirty years ago that I ?rst met Duccio Macchetto at the ?rst meeting of the newly formed Science Working Group of what was then called the Space Telescope project. We were there in slightly d- ferent roles, Duccio as the project scientist for the Faint Object Camera and I as an interdisciplinary scientist. Henk van de Hulst was also there as the of?cial rep- sentative of ESO. The approval of the project was the end result of a great deal of lobbying and politicking both in the USA and Europe, the European contribution proving essential to the approval process in the USA. Those interested in the nit- gritty of t...
This book covers the state-of-the-art of modern MALDI (matrix-assisted laser desorption/ionization) and its applications. New applications and improvements in the MALDI field such as biotyping, clinical diagnosis, forensic imaging, and ESI-like ion production are covered in detail. Additional topics include MS imaging, biotyping/speciation and large-scale, high-speed MS sample profiling, new methods based on MALDI or MALDI-like sample preparations, and the advantages of ESI to MALDI MS analysis. This is an ideal book for graduate students and researchers in the field of bioanalytical sciences. This book also: • Showcases new techniques and applications in MALDI MS • Demonstrates how MALDI is preferable to ESI (electrospray ionization) • Illustrates the pros and cons associated with biomarker discovery studies in clinical proteomics and the various application areas, such as cancer proteomics