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A Voice in the Wilderness
Why understanding evolution—the most reviled branch of science—can help us all, from fighting pandemics to undoing racism Evolutionary science has long been regarded as conservative, a tool for enforcing regressive ideas, particularly about race and gender. But in A Voice in the Wilderness, evolutionary biologist Joseph L. Graves Jr.—once styled as the “Black Darwin”—argues that his field is essential to social justice. He shows, for example, why biological races do not exist. He dismantles recent work in “human biodiversity” seeking genes to explain the achievements of different ethnic groups. He decimates homophobia, sexism, and classism as well. As a pioneering Black biologist, a leftist, and a Christian, Graves uses his personal story—his journey from a child of Jim Crow to a major researcher and leader of his peers—to rewrite his field. A Voice in the Wilderness is a powerful work of scientific anti-racism and a moving account of a trailblazing life.
Advances in DNA Sequence-Specific Agents
DNA sequence specificity is a sub-specialty in the general area of molecular recognition. This area includes macromolecular-molecular interactions (e.g., protein-DNA), oligomer-DNA interacitons (e.g., triple strands), and ligand-DNA interactions (e.g., drug-DNA). It is this latter group of DNA sequence specificity interactions that is the subject of Volumes 1 and 2 of Advances in DNA Sequence Specific Agents. As was the case for Volume 1, Part A also covers methodology, but in Volume 2 we include calorimetric titrations, molecular modeling, X-ray crystallographic and NMR structural studies, and transcriptional assays. Part B also follows the same format as Volume 1 and describes the sequence specificities and covalent and noncovalent interactions of small ligands with DNA.This volume is aimed in general at scientists who have an interest in deciphering the molecular mechanisms for sequence recognition of DNA. The methods have general applicability to small molecules as well as oligomers and proteins, while the examples provide general principles involved in sequence recognition.
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Helium
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