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Insulin-like growth factor (IGF)-I is a widely expressed growth factor with diverse effects on many tissues throughout development and in adult life. The purpose of this work is to provide detailed and updated information on the role of the growth hormone (GH)-IGF axis in fetal and postnatal development, as well as its physiological functions and implications in pathology.
The purpose of this book is to provide readers with an introduction to the fields of decision making, location analysis, and project and machine scheduling. The combination of these topics is not an accident: decision analysis can be used to investigate decision seenarios in general, location analysis is one of the prime examples of decision making on the strategic Ievel, project scheduling is typically concemed with decision making on the tactical Ievel, and machine scheduling deals with decision making on the operational Ievel. Some of the chapters were originally contributed by different authors, and we have made every attempt to unify the notation, style, and, most importantly, the Ievel...
Part of a series which provides autobiographical studies by individuals who are among contemporary leaders in the management discipline. Essays explore their experiences, and the factors and forces influencing their professional and personal development. Bibliographies of their work are included.
A guide to the field of dermatotoxicology. This edition includes fundamental information on the mechanisms of action of toxic substances on skin as well as practical information on the varied responses of skin to specific toxic substances and approaches to evaluating dermal toxicity. Other topics discussed include: hostile natural elements, such as ultraviolet radiation, poisonous plants, man-made detergents and chemicals; problems associated with chronic occupational skin exposure to toxic chemicals; animal alternative research programmes; carcinogenic and Photo Carcinogenic Potential Of Xenobiotic Chemicals; Oculotoxicity; Risk assessment and management; and cosmetic safety. Anatomical factors affecting barrier functions/ lipids of the permeability barrier/the skin immune system.