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A Definitive New Reference for the Latest Advances in B_12 Chemistry and Biochemistry Over the past decade, the field of B_12 research has been revolutionized by such major breakthroughs as the unraveling of the entire biosynthetic pathway for this important vitamin. This comprehensive compendium surveys the wealth of information that has accumulated, covering in one volume virtually all aspects of the field-from physical and inorganic chemistry to enzymology, microbiology, medicine, and diagnostic and therapeutic applications. Edited by Dr. Ruma Banerjee, a highly respected and active member of the B_12 community, this work provides B_12 researchers with a dependable and up-to-date referenc...
This third edition retains the general level and scope of earlier editions, but has been substantially updated with over 900 new references covering the literature through 2005, and 140 more pages of text than the previous edition. In addition to the general updating of materials, there is new or greatly expanded coverage of topics such as Curtin-Hammett conditions, pressure effects, metal hydrides and asymmetric hydrogenation catalysts, the inverted electron-transfer region, intervalence electron transfer, photochemistry of metal carbonyls, methyl transferase and nitric oxide synthase. The new chapter on heterogeneous systems introduces the basic background to this industrially important area. The emphasis is on inorganic examples of gas/liquid and gas/liquid/solid systems and methods of determining heterogeneity.
"Provides the latest research results and suggests new topics for interdisciplinary study of metal ions, catalysis, and biochemical systems. Second Edition highlights potential applications; includes new chapters on zinc and FeS clusters; presents new X-ray analysis of metalloenzymes; and more."
Calixarene chemistry, at the turn of the millennium, is a field approaching true maturity. In many areas, applications are real and important, and the arsenal of structures based on calixarenes provides tools effective in numerous areas of supramolecular chemistry. In this book, chapters contributed by a broad spectrum of international authors provide a variety of perspectives upon the progress and future of calixarene chemistry. Issues covered in depth include: Calixarene synthesis, with all its subtleties and sophistication. Forces at play in the inclusion of neutral and charged molecules by calixarenes. Theoretical analyses of calixarene properties. Dynamics and thermodynamics of calixarenes and their complexes. Nanocomposite construction based on calixarene aggregates. Calixarenes on surfaces. Analytical applications of calixarenes. Catalysis by calixarenes and their complexes. Resource recovery and waste treatment with calixarenes. New directions in calixarene chemistry. Hetero- and homo-calixarenes. Bioactive calixarenes. Coordination chemistry of calixarenes. Calixarenes in the solid state.
Here, H.-G. Schmalz and T. Wirth have put together a collection of current contributions on the most important topics in organic chemistry all in one handy book. Like its successful predecessors, this volume provides readers with numerous articles on the current state of synthetic methods and their applications. The wide range covered by nearly forty contributions ensures a concise overview of the latest developments in the field, whether they be new methods of C-C bond formation or racemization, asymmetric phase-transfer catalysis or stereoselective metathesis reactions, solid phase reactions or particularly elegant syntheses of challenging natural products. Throughout, the highly renowned authors guarantee the exceptionally high quality of the articles, making this an indispensable read for everyone wanting to stay abreast of developments in organic chemistry.
The first comprehensive coverage of all facets of the Claisen rearrangement and its variants. As such, this book helps synthetic chemists to exploit the vast potential of this elegant C-C linking reaction, discusses a wealth of catalytic options, and gives those more theory-minded chemists a detailed insight into the mechanistic aspects of the Claisen rearrangement. An invaluable source of information and a ready reference for all organic and catalytic chemists, as well as those working with/on organometallics, and in industry.
The most useful reactions of organonitro compounds in organic synthesis Compounds containing nitro groups are useful intermediates for the synthesis of natural products and other complex organic molecules. The Nitro Group in Organic Synthesis focuses on reactions that proceed under mild conditions, important functional groups that can be synthesized by conversion of nitro groups, and the stereoselectivity of reactions of nitro compounds. These issues are of great importance to practicing researchers in today's pharmaceutical, agrochemical, and fine chemical industries. The Nitro Group in Organic Synthesis also emphasizes environmentally-friendly methods for nitration, the importance of aliphatic nitro compounds, and modern preparation of nitro compounds. Other topics discussed include: * Henry reaction * Asymmetric Michael addition * Alkylation, acylation, halogenation, and related reactions of RNO2 * Substitution and elimination of NO2 and RNO2 The Nitro Group in Organic Synthesis is a useful resource for researchers and students in organic and medicinal chemistry.
A hernia is where an internal part of the body pushes through a weakness in the muscle or surrounding tissue wall. Hernias usually occur in the abdomen and there are several different types, each determined by its location within the abdomen. This book is an operative guide to laparoscopic hernia repair for practising and trainee surgeons. Beginning with an introduction and discussion on anatomy, the following section provides step by step guidance on the surgical repair of different types of hernia, and potential difficulties and complications. The final chapter provides a general overview of hernia, explaining classification, signs and symptoms, diagnosis, and treatment. The book includes two interactive DVD ROMs demonstrating surgical techniques as well as high quality photographs and illustrations. Key points Concise guide to laparoscopic hernia repair for surgeons and trainees Provides step by step guidance on surgical procedures for different types of hernia Covers potential difficulties and complications in surgery Includes two DVD ROMs demonstrating techniques and high quality photographs and illustrations
Comprehensive Organic Functional Group Transformations II (COFGT-II) will provide the first point of entry to the literature for all scientists interested in chemical transformations. Presenting the vast subject of organic synthesis in terms of the introduction and interconversion of all known functional groups, COFGT-II provides a unique information source documenting all methods of efficiently performing a particular transformation. Organised by the functional group formed, COFGT-II consists of 144 specialist reviews, written by leading scientists who evaluate and summarise the methods available for each functional group transformation. Also available online via ScienceDirect – featuring...
Hyper-Structured Molecules are topologically well-defined molecules in two or three dimensions, expected to show novel quantum effects in the molecular sequences. This book covers molecular designs of dendrimers, oligomers, hyperbranched polymers and/or high spin systems, molecular organizations and nanostructures, mesoscopic pattern formation, and