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Biomaterials for Brain Therapy and Repair
Prevalence of brain related diseases is expected to increase significantly in the next decades. Therefore, there is a vital need to develop effective, personalized models of human brain that can provide information about brain development, and the unique neurobiology of brain disorders. The use of biomaterials can play a strategic role for the future understanding and treatment of complex CNS diseases. Three-dimensional brain cultures have shown promise in disease modelling, cell transplantation and modulation of tissue repair.
Women in Biomaterials Science 2023
We are pleased to announce the launch of the 2nd Edition of "Women in Science: Biomaterials Science" Research Topic in Frontiers in Biomaterials Science. At present, less than 30% of all researchers worldwide are women and similar ratios are seen in the science community, particularly in the US. Long-standing biases and gender stereotypes are discouraging girls and women away from science-related fields, and STEM research in particular. Science and gender equality are, however, essential to ensure sustainable development as highlighted by UNESCO. In order to change traditional mindsets, gender equality must be promoted, stereotypes defeated, and girls and women should be encouraged to pursue STEM careers.
Targeted Drug Delivery
This volume looks at the latest techniques used to enable therapeutic molecules to be targeted for site-specific delivery. The chapters in this book discuss topics such as approaches to express biologically derived and synthetic nanocarriers; strategies to assist in nanocarrier targeting to specific cells and tissues; and methods for evaluating delivery and efficiency for new classes of agents. Written in the highly successful Methods in Molecular Biology series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls. Cutting-edge and comprehensive, Targeted Drug Delivery: Methods and Protocols is a valuable resource for anyone interested in understanding the diversity of methods used in this evolving field.
The Glutamate Receptors
This insightful and comprehensive book covers nearly every aspect of glutamate receptor structure and function for the working researcher and student. It condenses two previous landmark volumes into one easily accessible volume, and covers the extraordinary research and significant developments in the decade since the previous books were published. This includes the central role glutamate receptors play in neurotransmission.
Estrogens and Memory
"A book about the influence of estrogens on memory would have been unthinkable as recently as 30 years ago. Although a few small studies in the late 1970's reported a beneficial effect of estrogens on memory in human women (Hackman and Galbraith, 1976; Fedor-Freybergh, 1977), examination of the role of estrogens in memory did not truly capture more widespread attention until the pioneering work of Barbara Sherwin and colleagues in 1988 and beyond. In her initial paper, Sherwin showed that bilateral removal of the ovaries (aka surgical menopause) led to impaired short-term and long-term memory, whereas treatment of surgically menopausal women with estradiol alone, testosterone alone, or estra...
The Maze Book
This vibrant collection delivers a laboratory roadmap of testing cognition in the rodent. While rodents and mazes are the main center and focus of this book, many aspects in the field of learning and memory are discussed and detailed, spanning from the molecular to the human, with every chapter delivering a comprehensive review of historical milestones in order to provide context for past discoveries, new findings, and future studies. Didactic foundations, operational definitions, and theory, as well as practical experimental and apparatus set-up, data analysis, and interpretation instructions are included in the first part of the book, while part two contains step-by-step protocols, troubleshooting, and tips from experts in the field. Authoritative and inspirational, The Maze Book: Theories, Practice, and Protocols for Testing Rodent Cognition serves as a detailed and practical manual for scientists wishing to implement these tools in their laboratories and for scholars interested in this powerful field.
The Extragalactic Distance Scale
One of the hottest debates in astronomy and cosmology today concerns the value of the Hubble constant. This constant is of paramount importance since it fixes the size and age of the Universe. At a symposium at the Space Telescope Science Institute, experts from around the world presented the latest results from a plethora of techniques for determining the Hubble constant. The value has always been controversial, but at this meeting experts' results agreed for the first time to within about 20%. Based on the meeting, this book presents twenty-three specially written review articles. They provide a comprehensive account of the Hubble-constant debate with the latest results from gravitational lensing, supernovae and novae, the Tully-Fisher relation, the Sunyaev-Zeldovich effect, globular clusters, planetary nebulae, light echoes, and the Hubble Space Telescope Key Project. This timely volume provides a standard reference for graduate students and researchers in astronomy and cosmology.
The Coastal Everglades
Introduction -- The Everglades as icon -- Water, sustainability, and survival -- Ecosystem fragmentation and connectivity : legacies and future implications of a restored everglades -- The life of P : a biogeochemical and socio-political challenge in the Everglades -- Carbon cycles in the Florida coastal Everglades social-ecological system across scales -- Exogenous drivers : what has disturbance taught us? -- Back to the future : rebuilding the Everglades -- Re-imagining ecology through an Everglades lens.
Continental Marine
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