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Model Organisms
This Element presents a philosophical exploration of the concept of the 'model organism' in contemporary biology. Thinking about model organisms enables us to examine how living organisms have been brought into the laboratory and used to gain a better understanding of biology, and to explore the research practices, commitments, and norms underlying this understanding. We contend that model organisms are key components of a distinctive way of doing research. We focus on what makes model organisms an important type of model, and how the use of these models has shaped biological knowledge, including how model organisms represent, how they are used as tools for intervention, and how the representational commitments linked to their use as models affect the research practices associated with them. This title is available as Open Access on Cambridge Core.
The Life of a Virus
We normally think of viruses in terms of the devastating diseases they cause, from smallpox to AIDS. But in The Life of a Virus, Angela N. H. Creager introduces us to a plant virus that has taught us much of what we know about all viruses, including the lethal ones, and that also played a crucial role in the development of molecular biology. Focusing on the tobacco mosaic virus (TMV) research conducted in Nobel laureate Wendell Stanley's lab, Creager argues that TMV served as a model system for virology and molecular biology, much as the fruit fly and laboratory mouse have for genetics and cancer research. She examines how the experimental techniques and instruments Stanley and his colleagues developed for studying TMV were generalized not just to other labs working on TMV, but also to research on other diseases such as poliomyelitis and influenza and to studies of genes and cell organelles. The great success of research on TMV also helped justify increased spending on biomedical research in the postwar years (partly through the National Foundation for Infantile Paralysis's March of Dimes)—a funding priority that has continued to this day.
The Body Divided
Bodies and body parts of the dead have long been considered valuable material for use in medical science. Over time and in different places, they have been dissected, autopsied, investigated, harvested for research and therapeutic purposes, collected to turn into museum and other specimens, and then displayed, disposed of, and exchanged. This book examines the history of such activities, from the early nineteenth century through to the present, as they took place in hospitals, universities, workhouses, asylums and museums in England, Australia and elsewhere. Through a series of case studies, the volume reveals the changing scientific, economic and emotional value of corpses and their contested place in medical science.
Big Picture Bioethics: Developing Democratic Policy in Contested Domains
This book addresses the problem of how to make democratically-legitimate public policy on issues of contentious bioethical debate. It focuses on ethical contests about research and their legitimate resolution, while addressing questions of political legitimacy. How should states make public policy on issues where there is ethical disagreement, not only about appropriate outcomes, but even what values are at stake? What constitutes justified, democratic policy in such conflicted domains? Case studies from Canada and Australia demonstrate that two countries sharing historical and institutional characteristics can reach different policy responses. This book is of interest to policymakers, bioethicists, and philosophers, and will deepen our understanding of the interactions between large-scale socio-political forces and detailed policy problems in bioethics. asdf
The Ethics of Inheritable Genetic Modification
Is inheritable genetic modification the new dividing line in gene therapy? The editors of this searching investigation, representing clinical medicine, public health and biomedical ethics, have established a distinguished team of scientists and scholars to address the issues from the perspectives of biological and social science, law and ethics, including an intriguing Foreword from Peter Singer. Their purpose is to consider how society might deal with the ethical concerns raised by inheritable genetic modification, and to re-examine prevailing views about whether these procedures will ever be ethically and socially justifiable. The book also provides background to define the field, and discusses the biological and technological potential for inheritable genetic modification, its limitations, and its connection with gene therapy, cloning, and other reproductive interventions. For scientists, bioethicists, clinicians, counsellors and public commentators, this is an essential contribution to one of the critical debates in current genetics.
The Man Who Crucified Himself
The Man Who Crucified Himself is the story of Mattio Lovat’s self-crucifixion in Venice in 1805. It shows how the narrative of this sensational medical case was popularised in nineteenth-century Europe and appropriated by readers in debates on madness, suicide and religion.
Gender, Embodiment, and the History of the Scholarly Persona
This book investigates the historical construction of scholarly personae by integrating a spectrum of recent perspectives from the history and cultural studies of knowledge and institutions. Focusing on gender and embodiment, the contributors analyse the situated performance of scholarly identity and its social and intellectual contexts and consequences. Disciplinary cultures, scholarly practices, personal habits, and a range of social, economic, and political circumstances shape the people and formations of modern scholarship. Featuring a foreword by Ludmilla Jordanova, Gender, Embodiment, and the History of the Scholarly Persona: Incarnations and Contestations is of interest to historians,...
Fundamentals of the Stem Cell Debate
"What the editors have managed to accomplish with Fundamentals of the Stem Cell Debate is very significant. The book is well-informed, sophisticated, and attends to the moral and scientific complexities of stem cell research, rather than sweeping them under the rug. This book encompasses the complexities without sacrificing the other main virtue of the collection: to definitively illuminate the debate for all."—Jason Scott Robert, author of Embryology, Epigenesis, & Evolution: Taking Development Seriously
Oceans Under Glass
A welcome dive into the world of aquarium craft that offers much-needed knowledge about undersea environments. Atlantic coral is rapidly disappearing in the wild. To save the species, they will have to be reproduced quickly in captivity, and so for the last decade conservationists have been at work trying to preserve their lingering numbers and figure out how to rebuild once-thriving coral reefs from a few survivors. Captive environments, built in dedicated aquariums, offer some hope for these corals. This book examines these specialized tanks, charting the development of tank craft throughout the twentieth century to better understand how aquarium modeling has enhanced our knowledge of the ...
Patient-Centered Measurement
Patients often are asked to fill out questionnaires before or after going to the doctor's office or hospital. What is the point of these questionnaires? Why do the questions often seem irrelevant? Does it matter if patients fill them out or ignore them? This book addresses these questions while also providing historical context about how these questionnaires became so popular. These questionnaires, which philosopher Leah M. McClimans calls 'Patient-Centered Measures' have a fascinating history that combines the contemporary emphasis in medical ethics on patient-centered care with the contemporary preoccupation with evidence-based medicine (the idea that medical decisions should be based on empirical evidence). Patient-centered measures sit between these two concerns and thus serve as an excellent example of a medical technology for the twenty-first century.
