Welcome to our book review site go-pdf.online!
You may have to Search all our reviewed books and magazines, click the sign up button below to create a free account.
Women in Cancer Imaging and Image-directed Interventions: 2021
We are delighted to present the inaugural Frontiers in Oncology "Women in Cancer Imaging and Image-directed Interventions” series of article collections. At present, less than 30% of researchers worldwide are women. Long-standing biases and gender stereotypes are discouraging girls and women away from science-related fields, and STEM research in particular. Science and gender equality are, however, essential to ensure sustainable development as highlighted by UNESCO. In order to change traditional mindsets, gender equality must be promoted, stereotypes defeated, and girls and women should be encouraged to pursue STEM careers.
Functional Imaging of Early Markers of Disease
This is the second part which highlights the role that various imaging techniques play and/or might be able to play in detecting markers of disease. Cancer is often used as the example disease, but tumors exhibit many properties in common with other tissue, so it is possible to see how the techniques could be used in the diagnosis and management of other disease. There are also examples of the reverse of this flow of hypothesis and knowledge from one discipline to another. Magnetic resonance spectroscopy can be used to detect the chemical milieu of the nucleus being focused on, be it phosphorus-31 (Arias-Mendoza) or protons (He). Phosphorus is intimately involved in carbohydrate, phospholipi...
Circulating Tumor Cells
It is well recognized that blood could be the optimal site for evaluating cancer, allowing easy and repeated access for determining prognosis, establishing molecular targets, evaluating the efficacy of therapy, detecting the earliest signs of recurrence, and even detecting cancer at its earliest and most curable stages. The analysis of cancer through blood samples is now known as the liquid biopsy and has been a rich source of research and clinical application. There has been an explosion of interest and progress in liquid biopsy technologies since the first edition of this book. The second edition will expand its focus to now include not only circulating tumor cells (CTC), but also other em...
Image-guided Radiation Therapy
Image Guided Radiation Therapy (IGRT) is a true revolution in the field of radiation oncology. IGRT provides the unprecedented means of conforming does to the shape of the target tissues in 3-dimensions reducing the risk of complications thereby improving the quality of life of irradiated patients. Moreover, IGRT provides the means to deliver higher than conventional doses thus improving the chance of cure in these patients. Despite its established benefits, several barriers exist to the widespread clinical implementation of IGRT. In the past, great concerns existed regarding the large capital outlay needed for both software and hardware. This barrier is less relevant today given the increased reimbursements possible with IGRT. Today, the most significant barrier is education. IGRT is a fundamentally new approach to both treatment planning and delivery. Adoption of the IGRT approach entails new ways of thinking in regard to patient selection, treatment planning and quality assurance measures. Unfortunately, apart from a few University-based short courses, limited resources are available for the physician and physicist interested in learning IGRT.
Clinical Application of Stereotactic Body Radiotherapy (SBRT): Cranium to Prostate
Stereotactic radiosurgery is a relatively recent radiation technique initially developed using a frame-based system in 1949 by a Swedish neurosurgeon, Lars Leksell, for lesions not amendable to surgical resection. Radiosurgery is founded on principles of extreme radiation dose escalation, afforded by precise dose delivery with millimeter accuracy. Building upon the success of frame-based radiosurgery techniques, which were limited to cranial tumors and invasive head-frame placement, advances in radiation delivery and image-guidance have lead to the development of stereotactic body radiotherapy (SBRT). SBRT allows for frameless delivery of dose distributions akin to frame-based cranial stereotactic radiosurgery to both cranial and extra-cranial sites and has emerged as a important treatment strategy for a variety of cancers from the cranium to prostate. Herein we highlight ongoing investigations for the clinical application of SBRT for a variety of primary and recurrence cancers aimed at examining the growing clinical evidence supporting emerging roles for SBRT in the ever growing oncologic armamentarium.
Clinical Perfusion MRI
MR perfusion imaging is an area of major research interest and rapid clinical growth. Clinical Perfusion MRI: Techniques and Applications provides a concise and comprehensive review of the principles and applications of the field, covering dynamic susceptibility contrast, dynamic contrast enhancement, and arterial spin labeling imaging techniques. Principles of blood-volume and oxygenation imaging are included. The clinical applications of perfusion imaging in neurological disease and neuroscience are discussed – major topics including its use in imaging cerebrovascular disease and brain tumors and other neurological and neurodegenerative disorders. Non-neurologic applications are also covered with chapters on cardiac disease, breast cancer and other organ systems. Use of MR perfusion imaging in pediatrics is also discussed. Throughout the book case reports are included illustrating representative clinical examples. This book will be of interest to any clinician who uses MR perfusion imaging in their clinical practice, as well as researchers in the field of MRI.
