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Food or calorie restriction has been shown in many short-lived animals and the rhesus monkey to prolong life-span. Life-long nutrition studies are not possible in humans because of their long survival. Studies over two to six years in healthy adult humans have, however, shown that a 20% reduction in food or calorie intake slows many indices of normal and disease-related aging. Thus, it is widely believed that long-term reduction in calorie or food intake will delay the onset of age-related diseases such as heart disease, diabetes and cancer, and so prolong life. Over the last 20 or more years there has been a progressive rise in food intake in many countries of the world, accompanied by a ri...
"An engaging exploration of the unique history and biology of fasting-an essential component of many traditional health practices, religions, and philosophies, resurging in popularity today-perfect for readers of Breath by James Nestor and Why We Sleep by Matthew Walker.We fast all the time, even when we're not conscious of doing so. A fast manifests the idea of holding back, resisting the animal impulse to charge ahead. Its flip side is similarly everywhere: call it splurging, self-indulgence, or a variant of "self-care." Based on extensive historical, scientific, and cultural research and reporting, The Fast illuminates the numerous facets of this act of self-deprivation. John Oakes interv...
Is death inevitable? Until now, the history of mankind has been marked by this fatal fact. Religions, borders and progress are born from an ancient fear of death, comfort from this fear man often found only in religious paradigms. But according to José Luis Cordeiro and David Wood, the incontrovertible fact of death is no longer an absolute certainty - science and technology are preparing to tear down the final frontier: that of immortality. This accessible book provides insight into recent exponential advances in artificial intelligence, tissue regeneration, stem cell treatment, organ printing, cryopreservation, and genetic therapies that, for the first time in human history, offer a reali...
A groundbreaking examination of new scientific research that holds the secret to weight loss, increased strength, endurance, memory, and a healthier, longer life In The Longevity Factor, noted neuroscientist and surgeon Joseph Maroon, M.D., offers the definitive look at recent scientific breakthroughs identifying a group of natural substances -- including the much-publicized molecule resveratrol -- that can actually activate a specific set of genes in humans that promote a longer, healthier life. These substances, which make red wine, dark chocolate, and green tea good for us, appear to stave off a wide array of age-related diseases and keep us feeling young and vital. Resveratrol is the cen...
"How can you lose dramatic weight, reverse chronic conditions, and stay healthier longer? Flip the switch on your metabolism with intermittent fasting, protein restriction, and ketosis! Lose weight. Reverse Chronic Conditions. Live Healthier Longer. Within each of us is an ancient mechanism that eliminates toxic materials, initiates fat burning, and protects cells against stress. It's called autophagy, and when it's turned on, the complex operation can not only slow down the aging process, but can optimize biological function as a whole, helping to stave off all manner of disease-from diabetes to dementia-and affording us the healthy lifespan we never thought possible. So how can we activate this switch through diet? How frequently should we fast and for how long? Must we abstain from all foods or just specific macronutrients? What's the sweet spot between intermittent fasting, protein restriction, and ketogenic eating? Backed by a wealth of data, and with a practical program anyone can follow for lasting results, The Switch not only decodes the science of autophagy, but also teaches you how to control it and benefit from its profound impact"--
This book focuses on the three most important aspects of ageing research: nutrition, physical exercise and epigenetics. The contributors discuss ways that age-related epigenetic imprints such as DNA methylation and histone acetylation are modified by these two interventions. The emphasis on epigenetics helps to illuminate the underlying mechanisms of anti-ageing interventions, as ageing and disease are predominately epigenetic phenomena. Among the highlights are chapter-length discussion of such topics as: how anti-inflammatory action of calorie restriction underlies the retardation of ageing and age-related diseases (Chapter 3); epigenetic modification of gene expression by exercise (Chapter 5); the role of functional foods and their bioactive components in bone health (Chapter 8); and an account of the first decade of a study of calorie restriction in nonhuman primates, conducted by the National Institute on Ageing.
Geriatric medicine is one of the youngest medical specialities in Australia but is also one of the fastest growing. Geriatric medicine offers a more holistic approach to patient care than organ-based internal-medicine sub-specialities. Patient-centred interventions aim to allow the patient to function optimally. This textbook has been designed to inspire and inform students of geriatric medicine about the science and art of aged care. The book is structured to follow how geriatric-medicine clinicians approach patients who present with geriatric syndromes and must be assisted by systems of care. In an introductory part, overviews are provided of the biology of ageing, comprehensive geriatric ...
In September 2016, the National Academies of Sciences, Engineering, and Medicine convened a workshop to examine trends and patterns in aging and factors related to healthy aging in the United States, with a focus on nutrition, and how nutrition can sustain and promote healthy aging, not just in late adulthood, but beginning in pregnancy and early childhood and extending throughout the lifespan. Participants discussed the role of nutrition in the aging process at various stages in life, changes in organ systems over the lifespan and changes that occur with age related to cognitive, brain, and mental health, and explored opportunities to move forward in promoting healthy aging in the United States. This publication summarizes the presentations and discussions from the workshop.