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Mass Spectrometry in Drug Metabolism and Pharmacokinetics
This timely reference discusses mass spectrometry in drug metabolism and pharmacokinetic studies. With contributions by professionals from the pharmaceutical industry, this book begins with a review of current mass spectrometry techniques and applications, followed by discussions of various methods for using MS in drug metabolism studies and pharmacokinetics. Highlighting the critical importance of ADME studies for understanding how a drug is absorbed, distributed, metabolized, and excreted by the body, the book s focuses on the use of LC/MS and MALDI-MS. This is a valuable reference for scientists in the pharmaceutical industry, medicine, academia, and even those working in homeland defense.
Measuring Mass
Measuring Mass: From Positive Rays to Proteins is part of a celebration of fifty years of the Annual Conference on Mass Spectrometry and Allied Topics. As such, it is intended not only for practitioners of mass spectrometry but also for the lay reader interested in knowing more about the field. Many who practice the art and science of mass spectrometry are unaware of how the technique is applied outside their particular area of expertise. This short exposition will provide the practitioner and lay reader alike with an appreciation for the diverse applications of mass spectrometry in present-day scientific endeavors. Measuring Mass is also intended to celebrate the major events in the history...
Using Mass Spectrometry for Drug Metabolism Studies
The first edition of this now classic work helped to establish mass spectrometry as the premier tool for drug metabolism studies. Completely rewritten from start to finish, Using Mass Spectrometry for Drug Metabolism Studies, Second Edition brings medicinal chemists and mass spectrometry professionals up to speed with the rapid advances in the fiel
Proceedings of 7th World Congress on Mass Spectrometry 2018
June 20-22, 2018 Rome, Italy Key topics : Applications of Mass Spectrometry, New Approaches in Mass Spectrometry, Recent Advances and Development in Mass Spectrometry, Mass spectrometry imaging, Fundamentals of Mass Spectrometry, Ionization Techniques, Chromatography and High Performance Liquid Chromatography (HPLC), Mass Spectrometry in Proteome Research, Proteomics and its applications, Hyphenated Techniques, Spectroscopy, Maintenance, Troubleshooting, Data Analysis and Experimentation in Mass Spectrometry, Analytical Science and Separation Techniques,
Sample Preparation in LC-MS Bioanalysis
Revised and Expanded Handbook Provides Comprehensive Introduction and Complete Instruction for Sample Preparation in Vital Category of Bioanalysis Following in the footsteps of the previously published Handbook of LC-MS Bioanalysis, this book is a thorough and timely guide to all important sample preparation techniques used for quantitative Liquid Chromatography–Mass Spectrometry (LC-MS) bioanalysis of small and large molecules. LC-MS bioanalysis is a key element of pharmaceutical research and development, post-approval therapeutic drug monitoring, and many other studies used in human healthcare. While advances are continually being made in key aspects of LC-MS bioanalysis such as sensitiv...
Handbook of LC-MS Bioanalysis
Consolidates the information LC-MS bioanalytical scientists need to analyze small molecules and macromolecules The field of bioanalysis has advanced rapidly, propelled by new approaches for developing bioanalytical methods, new liquid chromatographic (LC) techniques, and new mass spectrometric (MS) instruments. Moreover, there are a host of guidelines and regulations designed to ensure the quality of bioanalytical results. Presenting the best practices, experimental protocols, and the latest understanding of regulations, this book offers a comprehensive review of LC-MS bioanalysis of small molecules and macromolecules. It not only addresses the needs of bioanalytical scientists working on ro...
Banks of the River Thillai
This gorgeous, funny novel paints a picture of a bygone era, depicting the changing society in Ceylon after Independence from the British in 1948. Three Tamil girl cousins, Gowry, Saratha and Buvana, grow up in the old-fashioned village of Kolavil in Eastern Sri Lanka near the beautiful River Thillai. As they approach womanhood, they each struggle in their own way to assert themselves in opposition to the strict traditions of Tamil culture and their powerful Grandma. Their idyllic village life is threatened by people and by events beyond their control. Meanwhile, the reader can get lost in a colourful world of flamingos, temple bells and coconut prawn curry.
Potential Microorganisms for Sustainable Agriculture
The number of potential microbes exploited commercially is scanty irrespective of their high number present in the diverse habitats. In recent years, they have shown successfulness in multifarious areas such as production of industrially viable products, organic chemicals, pharmaceuticals, recovery of metals, improvement and maintenance of environmental quality, and insect and pest control. The Twenty-three articles included here fall under three broad categories, namely, agricultural microbiology, industrial microbiology and bioremediation. The psychrophiles hold many biological secrets such as biochemical limits to macromolecular stability and the blueprints for constructing the stable mac...
