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Ischemic Injury
The World Stroke Organization reports that “stroke has already reached epidemic proportions. Globally1 in 4 adults over the age of 25 will have a stroke in their lifetime. 12.2 million people worldwide will have their first stroke this year, and 6.5 million will die as a result.” Ischemic strokes are the most common type of stroke, with about 87% of all strokes being ischemic strokes. This new volume addresses this epidemic by presenting detailed studies on ischemic injury, with emphasis on the molecular-level mechanisms and the role of signaling pathways in the body, their structure, and their mechanism of action. The book focuses on molecular pharmacology plans and explains the new are...
Life is unpredictable
Meenu and Ratan landed in Mumbai, were escorted to the city and were dropped at Kokilaben hospital. Let's see what is in store for her. Fighting cancer during pandemic was difficult but she fought well. With lots of positivity she won the battle. Admit, diagnosis, treatment, prognosis and follow up.
Revision Total Knee Arthroplasty
Edited by two leading authorities in the field, this volume is a technique-oriented "how-to" guide to an increasingly performed procedure, corrective surgery for the failed total knee arthroplasty. With more than 350 illustrations – 60 in full color.
Suicide
When everything happens according to your wish, it is good. But if not, then even better, because then it happens according to the God’s wish. Have you ever been through depression? Have you ever faced a break-up? Has life dragged you into loneliness overnight? Neil Bhanushali was once desperate to commit suicide. Against his wishes, he was saved at Green Islet island by a man called Chris Brown. His 13 Points and Final Chapter theory gave him hope and the will to fight. Learn how Neil defeats his demons and how Chris Brown’s 13 Points and Final Chapter theory helped him in Suicide: There is a way.
Walking the streets of society
WALKING THE STREETS OF SOCIETY: சமூகம் - ஓர் பார்வை At the verge of an era of development and stepping into the Artificial Intelligence, we are compelled to have our values and norms decked in our hearts with love jotted in our blood. "We" as society, have expanded like universe, evolved with seasons but when it comes to change, our society becomes frozen. “WALKING THE STREETS OF SOCIETY” fills the gap by unfolding the truth of undesirable reality in changing the society. WALKING THE STREETS OF SOCIETY is the reflection of today’s society. The script is a top notch collection of melancholic emotions expressed by protean writers on society in English and Tamil. The Book has been duly compiled by Ms. P. YUVASREE, who being a passionate writer, has co-authored several anthologies. With the experience gained she gives a go for her first compilation- "Walking the Streets of Society". With this motive, I welcome you all to step forward to WALK THE STREETS OF SOCIETY – One strongest step to string our minds for the betterment of our society!
Investigation and implementation of Shibboleth SSO authentication mechanism through a specific scenario
This work titled ‘Investigation and implementation of Shibboleth SSO mechanism through a case scenario’ presents, discusses, describes and explains the major aspects and concepts of Shibboleth protocol and provides two related prototypes implementations of the protocol within a set of chosen tools and environments. The implementation relies on the project client specifications and recommendations and therefore follows some imposed deployment infrastructures. The work report first focuses on the research investigation in Shibboleth concepts, its relationship with similar mechanisms and its particularities in the Single Sign On mechanism alongside with its federation principles. It also em...
Meta-analysis in Clinical Research: Principles and Procedures
This book provides conceptual information on the various processes involved in meta-analysis. It examines the importance of meta-analysis for the analyses of clinical data to draw a valid conclusion using suitable software. The initial sections of the book introduce meta-analysis, how to perform a systematic literature review (SLR), quality assessment of studies, extraction, and analysis of data. The subsequent section of the book contains information on advanced topics including, meta-regression, network meta-analysis, issues, mistakes, and future perspectives. In summary, the book provides a statistical method for combining the results of different studies on the same topic and resolving conflicts among studies. This book is written with the intent to allow a wide range of readers including students, researchers, and health care professionals, including physicians, nurses, pharmacists, and paramedical, and is also helpful for a beginner who would like to do a meta-analysis.
Resistance to Proteasome Inhibitors in Cancer
The book explores cutting-edge strategies to overcome proteasome inhibitor resistance, including the second generation 20S proteasome inhibitors, novel combinational therapies, and new targets in the ubiquitin-proteasome pathway (e.g., ubiquitin E3 ligases, deubiquitinases, 19S proteasomal ATPases, histone deacetylases, oxidative stress and proteotoxic stress pathways and pharmacogenomic signature profiling) in resistant cancer cells. The mechanisms of action and resistance of proteasome inhibitors, such as bortezomib and carfilzomib in human cancers, including multiple myeloma, mantle cell lymphoma, acute leukemia, and solid tumors are explored in depth in this volume. This timely volume unveils the most current discoveries of the mechanisms behind proteasome inhibitor resistance, which will help illuminate the future of cancer therapies.
Pro SQL Server Always On Availability Groups
This book is your field guide to planning, deploying, managing, and troubleshooting Always On Availability Groups. The Always On Availability Groups feature is an enterprise-level solution for high availability and disaster recovery. Always On provides a rich set of options that reduce overhead and resource usage and enable database administrators to implement and manage high availability and disaster recovery solutions far more easily than by implementing the log-shipping and database-mirroring solutions of the past. Pro SQL Server Always On Availability Groups shows how to reduce downtime, maximize application availability, and provide data protection. The goal is always to have your SQL S...
The Silicon Mind
The Silicon mind is a racy sci-fi thriller involving a very sophisticated neural chip implant by a robot on a human brain. It revolves around the intertwined lives of Ray, a leading neurosurgeon, sharp and flamboyant proprietor and driving force of Chetna, India's foremost coma clinic and Dr Aman Kapoor, reputed physician and accident victim who falls into a coma. Aman becomes Ray's unsuspecting guinea pig- Ray and his American collaborators successfully implant a silicon chip inside Aman's brain- true to the book's sci-fi genre, a robot does the operation! Aman wakes up- rejuvenated and changed forever. As Ray and his team expected, his brain has been enhanced to superlative degrees but his body suffers strange illnesses, a result of the conflict between the material chip and the corporeal brain. The story is about how Aman manages to trace his bizarre bodily symptoms and sudden miraculous healing powers to his brain operation at Chetna with help from Manasi, his psychiatrist, and her journalist friend, Ishan. Ray finally buckles to emotional pressure from Manasi and his own daughter, the irrepressible Sakshi and has to undo the wrong he had done by trying to play God.
