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Novel Drug Delivery Systems in the management of CNS Disorders
Novel Drug Delivery Systems in the Management of CNS Disorders provides a single source for information on drug delivery to the central nervous system. Written at graduate level, the book covers an extensive range of CNS disorders, including epilepsy, Parkinson’s, Alzheimer’s, Huntington’s, multiple sclerosis, schizophrenia, cerebral palsy, autism, ALS, and others. The book also presents the foundations of drug delivery to the brain and its challenges in the introductory part. The book’s final part is dedicated to clinical trials, and future prospects of the presented technologies. This book is a complete reference on overcoming the Brain-Blood Barrier and targeted drug delivery to the CNS. Drug delivery researchers in academia and corporate environments will benefit the most of this comprehensive reference.
Advanced Drug Delivery Systems for Colonic Disorders
Advanced Drug Delivery Systems for Colonic Disorders present the current state of the art methods for targeted drug delivery to the colon. These methods can prolong drug half-lives, improve bioavailability, optimize pharmacokinetics, and reduce medication dosing frequency. Chapters are written in a way that allows the audience to not only become familiar with the most recent advancement in the field, but to better understand them by referring to various illustrations, figures, and informative tables. The contents cover an overview of colonic diseases, the cellular and molecular mechanisms involved, current and traditional therapeutic approaches, biomaterials, oral drug delivery methods, targ...
Natural Polymeric Materials based Drug Delivery Systems in Lung Diseases
This book comprehensively reviews the recent developments of natural polymers for drug delivery systems in various lung disorders. The initial chapter provides a brief introduction to lung diseases with a focus on the current landscape of natural polymers and trends in understanding the disease pathology. Several chapters of the book devoted to the latest technologies and advances in drug delivery systems include practical solutions on designing more effective drug delivery systems based on natural polymers that can be used in the management of lung diseases. Further, the book presents biodegradable and bio-reducible- natural polymers- based drug delivery systems for lung diseases. Towards the end, the book examines future prospects and challenges of natural polymers-based drug delivery systems in combating lung diseases. This book is useful for phytochemists, formulation/drug delivery, biological and translational researchers and clinicians working in the field of lung disorders.
Targeting Cellular Signalling Pathways in Lung Diseases
The book comprehensively reviews and provides detailed insight into the cellular and molecular signalling mechanisms involved in pathophysiology of various respiratory diseases, towards developing effective therapeutic strategies in the management and treatment of lung disease. It also covers promising advances in the field of therapeutics that could lead to novel clinical therapies capable of preventing or reversing the disease features including novel strategies for targeting chronic lung diseases using advanced drug delivery systems. Importantly, the book examines the significance and relevance of the plant extracts and their constituents with therapeutic efficiencies against lung diseases. As such, the book offers a blend of translational, biological, chemical, and drug delivery aspects relevant to respiratory diseases, thus, offering a valuable resource for pulmonologists and translational researchers working in the field of pulmonary biology and respiratory medicine.
Martin's Physical Pharmacy and Pharmaceutical Sciences
Consistently revised and updated for more than 60 years to reflect the most current research and practice, Martin’s Physical Pharmacy and Pharmaceutical Sciences, 8th Edition, is the original and most comprehensive text available on the physical, chemical, and biological principles that underlie pharmacology and the pharmaceutical sciences. An ideal resource for PharmD and pharmacy students worldwide, teachers, researchers, or industrial pharmaceutical scientists, this 8th Edition has been thoroughly revised, enhanced, and reorganized to provide readers with a clear, consistent learning experience that puts essential principles and concepts in a practical, approachable context. Updated content reflects the latest developments and perspectives across the full spectrum of physical pharmacy and a new full-color design makes it easier than ever to discover, distinguish, and understand information—providing users the most robust support available for applying the elements of biology, physics, and chemistry in work or study.
Pharmacokinetics and Drug Metabolism in Canada: The Current Landscape
This book is a printed edition of the Special Issue "Pharmacokinetics and Drug Metabolism in Canada: The Current Landscape" that was published in Pharmaceutics
Gastrointestinal Variables and Drug Absorption
This book presents some of the state-of-the-art methods for the study of the gastrointestinal variables affecting oral drug absorption. Practical applications of new in vitro release/dissolution methods are presented, as well as in vitro permeability studies to explore segmental differences. The application of MRI methods for the study of colon physiology is presented to illustrate its potential applications in controlled release dosage form design. Some examples of successful in vitro–in vivo correlations show how implementing the gastrointestinal physiological variables in the new in vitro methods can improve the predictions of in vivo drug product performance. The book contains an updated review of the experimental, computational, and in vivo approaches for measuring intestinal permeability.
Nasal Drug Delivery
This book addresses the recent trends and clinical research being reported in last 5 to 10 years in the field of nasal drug delivery systems. In recent years, interest in using nasal passage as drug absorption site has received increased attention from formulation scientists. Nasal passages, even though a small surface area of the body as compared to other absorption passage such as Gastrointestinal tract or skin, show significant possibility for drug absorption at a quicker rate. There is also a possibility of delivering drugs to the brain using this passage and targeting drugs through the nasal passage. The book has 19 chapters addressing various aspects of nasal drug delivery systems such...
Generic Drug Product Development
In this era of increased pharmaceutical industry competition, success for generic drug companies is dependent on their ability to manufacture therapeutic-equivalent drug products in an economical and timely manner, while also being cognizant of patent infringement and other legal and regulatory concerns. Generic Drug Product Development: Solid Oral Dosage Forms, Second Edition presents in-depth discussions from more than 30 noted specialists describing the development of generic drug products—from the raw materials to the development of a therapeutic-equivalent drug product to regulatory approval. Major topics discussed include: Active pharmaceutical ingredients Experimental formulation de...
Nanotechnology in Nutraceuticals
Shows how nanotechnology can be used to develop better functional foods and nutraceuticals. Provides detailed knowledge of current development in nutraceuticals. Discusses marketing and consumer acceptance of nanomaterials. Reviews current governmental regulations.
