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The concept of credition represents an innovative research field at the interface of the natural sciences and the humanities addressing the nature of beliefs and believing. Credition signifies the integrative information processing that is brought about by neurophysiologically defined neural activity in the brain affording decision making. In analogy to cognition and emotion it is mediated by neural processes and constrains behavior by predictive coding. Three categories of beliefs have been defined on the background of evolutionary biology that can be differentiated linguistically. The goal of the collection of research papers is to provide an interdisciplinary discourse on an international...
Cancer, a global health crisis, is projected by WHO to cause 10 million deaths by 2020, with a mortality rate of one in six. This has spurred intensive research for innovative treatments. Cancer arises from genetic abnormalities triggering uncontrolled cell division, presenting distinct hallmarks. Both inherited and acquired mutations transform cell behavior, resulting in abnormal growth, reproduction, and death. Environmental toxins and spontaneous mutations contribute to genetic changes, while hereditary factors predispose some individuals. Despite rapid advancements in targeted treatments and immunotherapy, therapy resistance remains a formidable challenge due to the disease's heterogeneity. Understanding cancer biology is crucial for developing effective treatments. This book provides a comprehensive overview, covering basic cell biology, genetics, cancer development mechanisms, immune system involvement, diagnostic methods, treatment modalities, including emerging therapies, and challenges like drug resistance. Geared towards students and researchers in biology, medicine, and oncology, it offers vital insights into combating this complex disease.
This volume mainly contains information on the diagnosis, therapy, and prognosis of brain tumors. Insights on the understanding of molecular pathways involved in tumor biology are explained, which should lead to the development of effective drugs. Information on pathways (e.g., hedgehog) facilitates targeted therapies in cancer. Tumor models are also presented, which utilize expression data, pathway sensitivity, and genetic abnormalities, representing targets in cancer. For example, rat model of malignant brain tumors using implantation of doxorubicin with drug eluting beads for delivery is explained. The future of pathway-driven therapies for tumors is summarized. The importance of personal...
This book constitutes the refereed proceedings of the 7th International Conference on Information Technology in Bio- and Medical Informatics, ITBAM 2016, held in Porto, Portugal, in September 2016, in conjunction with DEXA 2016. The 9 revised long papers presented together with 11 poster papers were carefully reviewed and selected from 26 submissions. The papers address the following topics: biomedical data analysis and warehousing; information technologies in brain science; and social networks and process analysis in biomedicine.
Internationally renowned researchers discuss how the various parts of the brain process and integrate visual signals, providing up to date original findings, reviews, and theoretical proposals on visual processing. This book addresses the basic mechanisms of visual perception as well as issues such as neuronal plasticity, functional reorganization and recovery, residual vision, and sensory substitution. Knowledge of the basic mechanisms by which our brain can analyze, reconstruct, and interpret images in the external world is of fundamental importance for our capacity to understand the nature and causes of visual deficits, such as those resulting from ischemia, abnormal development, neuro-degenerative disorders, and normal aging. It is also essential to our goal of developing better therapeutic strategies, such as early diagnosis, visual training, behavioral rehabilitation of visual functions, and visual implants.
This is the fifth edition of the highly successful, classic textbook for bachelor and master courses, with over 20 % new material and the contents completely revised and updated. Using a minimum of mathematics, it explains the underlying theory of this most important spectroscopic technique in a thorough, yet readily understandable way, covering instrumentation and interpretation of the spectra. It presents all students need to know about 1D, 2D-NMR, solid state and dynamic NMR spectroscopy, as well as NMR imaging, all illustrated by examples for maximum clarity. All the sections include sub-chapters that focus on applications taken from organic, macromolecular, polymer and biochemistry. A must for students and lecturers in chemistry, biochemistry, pharmacy, and life sciences, as well as for spectroscopists.
The two-volume set LNAI 8397 and LNAI 8398 constitutes the refereed proceedings of the 6th Asian Conference on Intelligent Information and Database Systems, ACIIDS 2014, held in Bangkok, Thailand, in April 2014. The 125 revised papers presented were carefully reviewed and selected from 300 submissions. The papers address the following topics: natural language and text processing, intelligent information retrieval, semantic Web, social networks and recommendation systems, intelligent database systems, decision support systems, computer vision techniques, and machine learning and data mining. The papers are organized in topical sections on multiple model approach to machine learning, MMAML 201...
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