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"When P.V. Narasimha Rao became the unlikely prime minister of India in 1991, he inherited a nation adrift. Despite lacking the support of his people, party or parliament, India's Deng Xiaoping reinvented his country. Relying on Rao's private papers and over a hundred interviews, this biography is a must-read for anyone interested in the transformation of India"--
Infectious diseases are still leading cause of mortality around the world. Of particular importance in this regard are the intracellular pathogens, which dwell inside the host and manipulate host’s machinery for their growth. These include pathogens like Brucella abortus, Listeria monocytogenes, Chlamydia trachomatis, Coxiella burnetii, Mycobacterium tuberculosis, Salmonella enterica, etc. These pathogens have evolved multiple mechanisms to survive in intracellular niche. The host in turn tries to reprogram its activities to combat their growth. This host-pathogen co-evolution warrants detailed study to probe the ever-changing virulence repertoire of the pathogen, that can be used for pathogen targeting. Through this topic, we would like to explore the lesser explored area of host pathogen interactions. Studying host-pathogen crosstalk at their interface will help us in understanding this complex biology and might prove beneficial in development of new therapeutic targets. Understanding the holistics of host-pathogen interaction, will pave way for development of host-directed therapies.
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After the drug discovery and development process, designing suitable formulations to safely deliver the optimum dose, while avoiding side effects, has been a constant challenge, especially when drugs are very toxic and have poor solubility and undesirable clearance profiles. With recent advances in synthetic technologies, nanoparticles can be custom-made from a variety of advanced materials to mimic the bioenvironment and can be equipped with various targeting and imaging moieties for site-specific delivery and real-time imaging. Drug Delivery Using Nanomaterials covers advancements in the field of nanoparticle-based drug-delivery systems, along with all the aspects needed for a successful a...
This book reviews recent advances in the molecular and infection biology, pathology, and molecular epidemiology of Mycobacterium tuberculosis, as well as the identification and validation of novel molecular drug targets for the treatment of this mycobacterial disease. Despite being completely curable, tuberculosis is still one of the leading global causes of death. M. tuberculosis, the causative organism – one of the smartest pathogens known – adopts highly intelligent strategies for survival and pathogenesis. Presenting a wealth of information on the molecular infection biology of M. tuberculosis, as well as nontuberculous mycobacteria (NTM), the book provides an overview of the functio...
This book focuses on a close analysis of selected speeches of Winston Churchill in the House of Commons and some of the responses from fellow MPs from the middle of 1940 to the death of Churchill in 1965, speeches in war and peace, and concentrates on foreign affairs. The book will appeal to those interested in Churchill, freedom, tyranny, diplomacy, war and conflict, democracy, politics, the Second World War, the Cold War, Britain, Canada, the United States, the British Empire and Commonwealth, Europe, France, Asia, Germany, Japan, totalitarianism, Parliament, legislative assemblies, rhetoric, language, style, speech-writing, oral and written communication, literature, history and other areas. The debate between autocracy (tyranny, totalitarianism) and democracy is in those times and ours, with many parallels, chilling. Churchill was key to our world history and is a key to understanding what is at stake in the world now.
The International Conference on Innovations in Biotechnology and Life Sciences (ICIBLS), 2020 was hosted by Delhi Technological University (formerly known as Delhi College of Engineering) virtually between 18th Dec - 20th Dec 2020. The three-day virtual conference witnessed a total of 1200 participants across different parts of the globe. The conference also provided a platform to 20 participants to present their innovative research work covering broad topics like Bioinformatics, Cancer Biology, Cell Biology, Disease Detection, Environmental Biotechnology, Food Technology, Immunology, Microbiology, Nanotechnology, Neuroscience, and Plant Biotechnology. In addition to this,13 national and int...
The Fifth Edition of Bioethics and the Law takes a multidisciplinary approach that combines legal discussion with jurisprudential, philosophical, and sociological materials. Strong expressions of different points of view highlight debates about bioethical issues. The text underscores the need to mediate between the law's focus on broad rules and the bioethicist's concern with context and detail. Bioethics and the Law supplements the traditional focus of bioethics on the interest of the individual with a second focus on the broader developments that shape healthcare. Connecting broad public healthcare issues to concerns of the individual patient/healthcare consumer, the text promotes understa...