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Handbook of Research on Systems Biology Applications in Medicine
"This book highlights the use of systems approaches including genomic, cellular, proteomic, metabolomic, bioinformatics, molecular, and biochemical, to address fundamental questions in complex diseases like cancer diabetes but also in ageing"--Provided by publisher.
Systems Biology in Practice
Presenting the main concepts, this book leads students as well as advanced researchers from different disciplines to an understanding of current ideas in the complex field of comprehensive experimental investigation of biological objects, analysis of data, development of models, simulation, and hypothesis generation. It provides readers with guidance on how a specific complex biological question may be tackled: - How to formulate questions that can be answered - Which experiments to perform - Where to find information in databases and on the Internet - What kinds of models are appropriate - How to use simulation tools - What can be learned from the comparison of experimental data and modeling results - How to make testable predictions. The authors demonstrate how mathematical concepts can illuminate the principles underlying biology at a genetic, molecular, cellular and even organism level, and how to use mathematical tools for analysis and prediction.
Systems Biology and Computational Proteomics
This book constitutes the thoroughly refereed post-proceedings of two joint RECOMB 2006 satellite events: the Second Annual Workshop on Systems Biology, RSB 2006, and the First Biennial Workshop on Computational Proteomics, RCP 2006, held in San Diego, CA, USA in December 2006. The papers cover various aspects of systems biology and explore the use of computational mass spectrometry in various proteomic applications.
Web-Based Applications in Healthcare and Biomedicine
Web-based applications provide the power of desktop and server applications with the exibility and accessibility of the web. Using web browsers, users can securely access applications from anywhere within the reach of the company intranet or extranet. The special issue strives to explore the advanced web-based information systems and database applications in healthcare area. Healthcare organizations are undergoing major reorganizations and adjustments to meet the increasing demands of improved healthcare access and quality, as well as lowered costs. As the use of information technology to process medical data increases, much of the critical information necessary to meet these challenges is b...
Haplotyping
This book aims to be an introduction to haplotype information for both the wet and dry labs. Chapters detail co-barcoding and linked-reads based methods, third generation sequencing based methods, Hi-C based methods, single-cell and Strand-seq, and methods for using haplotype data once obtained. Written in the successful Methods in Molecular Biology series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible protocols, and notes on troubleshooting and avoiding known pitfalls. Authoritative and cutting-edge, Haplotyping: Methods and Protocols aims to provide compréhensive and accessible methods to undergraduate, graduate, and established scientists.
The Noughties Brought to Book
Why music doesn't add up, what The Simpsons can teach us about science, whether Juana la Loca wasn't crazy after all, and what's behind the gaseous veil of Saturn's moon Titan ' these are just some of the questions addressed in the more than 70 reviews and essay reviews from the years 2000 to 2009 collected in this volume. They cover books about science, ranging from the academic to the popularized kind, but there are also books about cultural topics and even a few novels scattered in for good measure. Most of these books reviewed haven't found a massive amount of attention, although some of them should have, at least in the reviewer's opinion. And even if the book under review wasn't all that good, the format of an essay review allows the author to have a go at presenting the subject matter his own way. All in all, a reflection of what happened during the noughties in the worlds of science and culture, and off the beaten track.
Research in Computational Molecular Biology
Zusammenfassung: This book constitutes the proceedings of the 28th Annual International Conference on Research in Computational Molecular Biology, RECOMB 2024, held in Cambridge, MA, USA, during April 29-May 2, 2024. The 57 full papers included in this book were carefully reviewed and selected from 352 submissions. They were organized in topical sections as follows: theoretical and foundational algorithm contributions and more applied directions that engage with new technologies and intriguing biological questions
Emerging Bioinformatic Tools in Toxicogenomics
Toxicogenomics was established as a merger of toxicology with genomics approaches and methodologies more than 15 years ago, and considered of major value for studying toxic mechanisms-of-action in greater depth and for classification of toxic agents for predicting adverse human health risks. While the original focus was on technological validation of in particular microarray-based whole genome expression analysis (transcriptomics), mainly through cross-comparing different platforms for data generation (MAQC-I), it was soon appreciated that actually the wide variety of data analysis approaches represents the major source of inter-study variation. This led to early attempts towards harmonizing...
Analysing Gene Expression
This book combines the experience of 225 experts on 900 pages. Scientists worldwide are currently overwhelmed by the ever-increasing number and diversity of genome projects. This handbook is your guide through the jungle of new methods and techniques available to analyse gene expression - the first to provide such a broad view of the measurement of mRNA and protein expression in vitro, in situ and even in vivo. Despite this broad approach, detail is sufficient for you to grasp the principles behind each method. In each case, the authors weigh up the advantages and disadvantages, paying particular attention to the automated, high-throughput processing demanded by the biotech industry. Complet...
Research in Computational Molecular Biology
This book constitutes the proceedings of the 24th Annual Conference on Research in Computational Molecular Biology, RECOMB 2020, held in Padua, Italy, in May 2020. The 13 regular and 24 short papers presented were carefully reviewed and selected from 206 submissions. The papers report on original research in all areas of computational molecular biology and bioinformatics.
