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The condition of prolonged obstructive jaundice with patent bile ducts was first described in 1851 by Addison and Gull of Guy's Hospital, London. The term primary biliary cirrhosis (PBC) was defined in 1950 by Ahrens and colleagues of the Rockefeller Institute, New York. The condition was considered rare but this changed in 1965 with the discovery of a definitive diagnostic serum mitochondrial antibody test and the recognition that a raised serum alkaline phosphatase value, often discovered incidentally, could be a diagnostic pointer. If the diagnosis is made earlier, the end stages are rarely reached as death is replaced by liver transplantation. On November 6th 1997, in Chicago, an Interna...
A comprehensive guide to diseases of the immune system, listing names, symptoms, research, treatments available and more.
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Contains contributions dedicated to intracellular mechanisms leading to cholestasis. The book emphasizes the plasma membrane in order to explain altered uptake and secretion of bile salts.
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Whereas other textbooks mix a clinical approach with large amounts of the basic science of gastroenterology, this book concentrates on providing practicing gastroenterologists with 100% clinically focused, evidence-based chapters on how to correctly diagnosis and treat all disorders of the digestive tract. Once again, the book is divided into 4 clear parts: Symptoms, Syndromes and Scenarios; Diseases of the Gut and Liver; Primer of Diagnostic Methods; and Primer of Treatments. An accompanying website contains more than 85 high-definition surgical videos of diagnostic and therapeutic endoscopic procedures, 300 MCQs written to mirror the American College of Gastroenterology postgraduate course exams, more than 35 management protocol charts for different diseases, and 850+ illustrations for use in scientific presentations.
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