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Molecular Mechanisms Underpinning the Development of Obesity
Obesity is a multi-factorial disease, in which an excess of accumulated body fat can reach levels capable of affecting health. It results from an interplay between environmental factors, eating behavior, genes, epigenetics, and neuronal stimuli. The main aim of this book is to provide a state-of-the-art revision about the molecular mechanisms underpinning the development of obesity, reviewing the current knowledge in areas like monogenic and polygenic obesity forms, but also providing an updated view of the emerging knowledge about epigenetics, nutrigenomics, and neuronal aspects that also contribute to obesity.
Pura vida
In Pura vida (Life is good)Spanish is more than vocabulary and grammar, just as Spanish-speaking cultures are more than products and practices. In this learner-centered introductory program, the authors’ commitment to a methodology based on true-to-life experiences brings Spanish to life. Pura vida is the discovery of a Spanish-speaking world through the experiences of real people who share anecdotes and reflections on those experiences. Students relate to these people and make deeper, more meaningful connections between language and culture, and acquire Spanish with an unparalleled sense of personal engagement. In this 12-chapter introductory program, students don’t only learn Spanish for real life, but also from real life. They discover that there is not just one homogeneous Hispanic culture, but rather that each Spanish-speaking country has its own rich, unique culture and that the people who live in these countries speak one common language with different accents, characteristics, and idiosyncrasies. The program offers truly seamless integration of cultural notions and language instruction and features 100% contextualized and personalized activities.
Count on Me
Beloved bestselling Latino authors, including Esmeralda Santiago, Carolina De Robertis, and Luis Alberto Urrea share moving personal stories of the many ways that sisterly bonds have powerfully impacted their lives. Friendships can bring us peace, fill the emotional shortcomings in our romantic relationships, and help us remember what lies deep inside every one of us. For more than twelve years, the international organization Las Comadres Para Las Americas™ has been bringing together thousands of Latinas to count on, lean on, help, and advise one another. Comadre is a powerful term. It encompasses the most important relationships that exist between women: best friends, confidants, coworker...
Cytoskeleton
The cytoskeleton is a highly dynamic intracellular platform constituted by a three-dimensional network of proteins responsible for key cellular roles as structure and shape, cell growth and development, and offering to the cell with "motility" that being the ability of the entire cell to move and for material to be moved within the cell in a regulated fashion (vesicle trafficking). The present edition of Cytoskeleton provides new insights into the structure-functional features, dynamics, and cytoskeleton's relationship to diseases. The authors' contribution in this book will be of substantial importance to a wide audience such as clinicians, researches, educators, and students interested in getting updated knowledge about molecular basis of cytoskeleton, such as regulation of cell vital processes by actin-binding proteins as cell morphogenesis, motility, their implications in cell signaling, as well as strategies for clinical trial and alternative therapies based in multitargeting molecules to tackle diseases, that is, cancer.
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