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Collaborative Innovation in Drug Discovery
Can academia save the pharmaceutical industry? The pharmaceutical industry is at a crossroads. The urgent need for novel therapies cannot stem the skyrocketing costs and plummeting productivity plaguing R&D, and many key products are facing patent expiration. Dr. Rathnam Chaguturu presents a case for collaboration between the pharmaceutical industry and academia that could reverse the industry's decline. Collaborative Innovation in Drug Discovery: Strategies for Public and Private Partnerships provides insight into the potential synergy of basing R&D in academia while leaving drug companies to turn hits into marketable products. As Founder and CEO of iDDPartners, focused on pharmaceutical in...
Innovative Approaches in Drug Discovery
Despite considerable technological advances, the pharmaceutical industry is experiencing a severe innovation deficit, especially in the discovery of new drugs. Innovative Approaches in Drug Discovery: Ethnopharmacology, Systems Biology and Holistic Targeting provides a critical review and analysis of health, disease and medicine, and explores possible reasons behind the present crisis in drug discovery. The authors illustrate the benefits of systems biology and pharmacogenomics approaches, and advocate the expansion from disease-centric discovery to person-centric therapeutics involving holistic, multi-target, whole systems approaches. This book lays a path for reigniting pharmaceutical inno...
Advances in Combinatorial Chemistry & High Throughput Screening
Advances in Combinatorial Chemistry & High Throughput Screening, is an e-book series comprising updated research articles previously published in the impact factor journal, Combinatorial Chemistry & High Throughput Screening (CCHTS). A wide range of topics are covered by these articles including chemical biology, high throughput screening, combinatorial chemistry, chemoinformatics, laboratory automation and compound management. This series is, therefore, a testament to CCHTS contributions in advancing drug discovery on full throttle. This eBook series opens up a new avenue for rapid access for readers – including academic researchers and industry professionals - to a focused collection of highly regarded contributions in the field.
The Core Model
The Core Model: A Collaborative Paradigm for the Pharmaceutical Industry and Global Health Care develops the innovative core model, an organizational research and design paradigm and economic theory that proposes a collaborative approach to resolving global health issues and improving the productivity of drug development. The model proposes that scientific collaboration does not occur in an unstructured manner, but actually takes place within a highly structured order where knowledge is transferred, integrated and finally translated into commercial products. An understanding of this model will help solve the global pharmaceutical industry ́s productivity problems and address important globa...
Ethnobotany and Ethnopharmacology of Medicinal and Aromatic Plants
Medicinal and aromatic plants are beneficial to human health. Plant-derived molecules possess biological activities that can be used to prevent many infectious diseases and metabolic disorders. Ethnobotany and Ethnopharmacology of Medicinal and Aromatic Plants summarizes techniques and methods used to study the biological activities of plant-derived extracts and compounds to study ethnobotanical and ethnopharmacological features of medicinal and aromatic plants. This book: Includes computational approaches to study the pharmacological properties of biomolecules in medicinal and aromatic plants. Details methods in ethnopharmacology including chromatographical and analytical techniques. Demons...
Traditional Medicines in Drug Discovery and Development
This comprehensive book, comprising 20 chapters contributed by respected academics in their respective fields, highlights the immense contribution of traditional medicine to the discovery and development of modern drugs. Each chapter provides in-depth details, stimulating experts to further explore the flora used in traditional medicines and inspiring younger investigators to delve into the mysterious world of secondary metabolites in their quest for novel molecules. This book is of immense value to scientists, academicians, researchers, and students alike, making it a valuable addition to personal collections and libraries.
Commentaries in Plant Science
Commentaries in Plant Science, Volume 2 is a collection of papers that reviews developments in the pure and applied science of plants. One paper discusses the role of supercooling in the winter survival mechanism of and ecological distribution of many plant communities. Another paper evaluates the Cholodny-Went theory of shoot geotropism that there is strong evidence in auxin redistribution occurring in a rapid manner to cause geotropic curvature. The magnitude of auxin redistribution is too rare to cause differential growth. Some insect pests have specific nutritional requirements and well-developed mechanisms for selecting their plant host. One paper enumerates the benefits of using insect...
Handbook of Drug Screening
Building upon the foundation of basics discussed in the previous edition, the Second Edition provides a more in-depth look at the latest methods and technologies of advanced drug screening, an essential function of drug discovery. With extensively updated content and 21 new chapters, this text examines:quality and efficiency of drug target validati
Photosynthesis Bibliography
The bibi iograp hy includes papers in a l I fields of photosynthesis research - from stu dies of model biochemical and biophysical systems of t he photosynt hes is mechanism to primary prod ucti on studied by t he so-ca Ile d growth analysis . In addition to papers devoted enti rel y to photosynth es is, papers on other topics are inc luded if t hey con t ai n data on photosynthetic activity, photorespiration, chloroplast structure, chlo rophylland carotenoid synthesi s and destruction, eta., or if they conta in valuable methodological information (measurement of selected environmentaI factars, leaf area, eta.) . In many branches it has been difficult to defi ne th e limits of int erest for photosynthesis researchers. This problem has arisen e. g. in topics deal ing with t he transfer of gases, where - in addition to t he papers on ca rbon dioxide transfe r - so me pape rs on water vapour transfer are included, these being of general appl icat ion or bringing new approaches . On th e other hand, m any papers deal ing wit h the anatomy and phys io logy of stomata have been omitted, if the aspect of ca rbon dioxide or water vapour exchange has not been discussed.
