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This book is based on the papers delivered at an International Workshop on Multiple Sclerosis held in Erice, Italy from 29th August to 1st September 1983. The Meeting was organized with great efficiency in the delightful setting of the Centro di Cultura Scientifica Ettore Mahorana, by its Director, Antonino Zichichi, and was directed by the Editors of the Proceedings and by Professor C. Alvisi of the University of Bologna. The emphasis was deliberately on the contributions of laboratory science to the understanding of mUltiple sclerosis, its etiology, pathogenesis, diagnosis and treatment. Where so much is unknown, disagreement was expected and indeed welcome, and it is regrettable that it w...
Multiple Sclerosis: Advances in Research and Treatment: 2011 Edition is a ScholarlyPaper™ that delivers timely, authoritative, and intensively focused information about Multiple Sclerosis in a compact format. The editors have built Multiple Sclerosis: Advances in Research and Treatment: 2011 Edition on the vast information databases of ScholarlyNews.™ You can expect the information about Multiple Sclerosis in this eBook to be deeper than what you can access anywhere else, as well as consistently reliable, authoritative, informed, and relevant. The content of Multiple Sclerosis: Advances in Research and Treatment: 2011 Edition has been produced by the world’s leading scientists, engineers, analysts, research institutions, and companies. All of the content is from peer-reviewed sources, and all of it is written, assembled, and edited by the editors at ScholarlyEditions™ and available exclusively from us. You now have a source you can cite with authority, confidence, and credibility. More information is available at http://www.ScholarlyEditions.com/.
CNS Demyelinating Autoimmune Diseases: Advances in Research and Treatment: 2011 Edition is a ScholarlyBrief™ that delivers timely, authoritative, comprehensive, and specialized information about CNS Demyelinating Autoimmune Diseases in a concise format. The editors have built CNS Demyelinating Autoimmune Diseases: Advances in Research and Treatment: 2011 Edition on the vast information databases of ScholarlyNews.™ You can expect the information about CNS Demyelinating Autoimmune Diseases in this eBook to be deeper than what you can access anywhere else, as well as consistently reliable, authoritative, informed, and relevant. The content of CNS Demyelinating Autoimmune Diseases: Advances in Research and Treatment: 2011 Edition has been produced by the world’s leading scientists, engineers, analysts, research institutions, and companies. All of the content is from peer-reviewed sources, and all of it is written, assembled, and edited by the editors at ScholarlyEditions™ and available exclusively from us. You now have a source you can cite with authority, confidence, and credibility. More information is available at http://www.ScholarlyEditions.com/.
This book comprehensively reviews the current state of clinical trial methods in multiple sclerosis treatment, providing investigators, sponsors and specialists with current knowledge of outcome measures and study designs for disease and symptom management. The status of the rapidly evolving field of disease-modifying drugs is presented, with emphasis on the most promising therapies currently being tested. Experts discuss disease and symptom management for MS subtypes, including neuromyelitis optica and pediatric MS. In addition, key scientific advances in MS pathology, genetics, immunology and epidemiology are presented. The fourth edition has been extensively revised, featuring more than 50% new material. All chapters have been substantially updated to provide current information on rapidly evolving topics and this volume contains 15 new chapters, reflecting the growth of the field in recent years. This book is an essential reference for practitioners caring for MS patients, investigators planning or conducting clinical trials, and clinical trial sponsors.
Multiple sclerosis is an unique disease with a tremendous impact on social life in countries with moderate climates. Its cause is unknown. In recent years however hopes have been raised that the disease might be fought, and possibly cured. With the disappearance of poliomyelitis as the main paralyzing disease multiple sclerosis has taken its place as the single disease that is responsible for paralyzing the young with an incurable affliction of long duration, for social disruption and for an 1 economic impact that is estimated to be higher than heart disease • A multi-national, mUlti-disciplinary approach to this extremely disabling disease is urgently needed in this phase of hopeful scientific developments. The Commission of the European Communities therefore sponsored a Con ference on Multiple Sclerosis Research in Europe on 29,30 and 31 January 1985 in Nijmegen, The Netherlands, with the aim of formulating practical proposals for such cooperation in the Communities. This volume contains the papers read at that conference.
This textbook examines the most important aspects of multiple sclerosis that impact on clinical trial design, on the development of new disease therapies and on patient care. The international team of contributors discuss the clinical course of multiple sclerosis, its clinical heterogeneity, the presence of subclinical disease activity which occurs during the early stages of the disease. Multiple sclerosis presents clinical challenges: from unexpected and irregular relapses to profressive deterioration.
Since its presentation by G.N. Hounsfield at the second Congress of the European Association of Radiology in Amsterdam in June 1971, "Computerised Trans verse Axial Tomography" which became later on "Computerised Axial Tomography (CAT)" then simply "Computed Tomography (CT)" has developed extremely rapidly. Many papers have appeared in a short time, pointed out the substantial advantages of this new technique and precisely describing the characteristic images obtained. The number of devices is already considerable and their evolution tends towards the improvement of the quality of images and the shortening of exploration time. It is not an exaggeration to say that there is no longer any Neuroradiology without computed tomography. Does that mean that this new technique is infallible and that classical neuroradiological techniques are due to disappear in the near future? Experience shows that if certain techniques, such as gas encephalography, 'are less frequently employed since CT, others, such as cerebral angiography, are still commonly required.
First multi-year cumulation covers six years: 1965-70.
At the annual meetings of the International Federation of Multiple Sclerosis Socie ties (IFMSS) the representatives of the national MS societies of numerous countries assemble for discussions and reports on work accomplished, under way, and to be undertaken in the future. In addition to publicity work, education, and patient ser vices, there has been an increasing interest in obtaining first hand, reliable, and re alistic information not only on the medical problems relevant to diagnosis, treat ment, and the management of MS, but also on progress in the difficult field of MS research. For this purpose the International Medical Advisory Board (IMAB) was founded. In the past years its members ...