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The calcitonin gene-related peptide family
In 1925, J. B. Collip (1925) reported that extracts of parathyroid gland contained an activity that raised calcium levels in the blood of parathyroidectomized animals, and suggested that this was due to a hormone produced in the parathyroid gland. The story of parathyroid hormone discovery was indicative of ever-increasing sophistication in sample preparation and protein isolation techniques. This paper resolved earlier controversies over the function of the parathyroid glands and c- trol of blood calcium. The year 1961 was a banner year for parathyroid research, in which the peptides parathyroid hormone and calcitonin were purified, and in which it was suggested that calcitonin could lower ...
NPY Family of Peptides in Neurobiology, Cardiovascular and Metabolic Disorders: from Genes to Therapeutics
The NPY-family of peptides encompasses several groups of neurotransmitters and hormones, which exert diverse biological and pathological actions that bear on all major vital systems. The recognition of the role of NPY in stimulation of food intake has already resulted in discovery of potent and selective NPY receptor Y-5 antagonists which are in clinical development for obesity while NPY Y1 receptors are targeted for cardiovascular indications. Research into the multiple functions of NPY and its receptors in neurological and affective disorders are also actively pursued. This book is a unique compilation of the most recent breakthroughs in NPY/PYY neurobiology, cardiovascular and metabolic disorders, written by internationally renowned experts with the objective to synthesize leading concepts and data in support for translational medicine.
Focus on Neuropsychology Research
Neuropsychology is the study of brain-behaviour relationships and examines such domains of cognitive functioning as memory, attention, visual-perceptual abilities, language and intellectual function. It is strongly scientific in its approach and shares an information processing view of the mind with cognitive psychology and cognitive science. It is one of the most eclectic of the psychological disciplines, overlapping at times with areas such as neuroscience, philosophy (particularly philosophy of mind), neurology, psychiatry and computer science (particularly by making use of artificial neural networks).
Critical Neuroscience
Critical Neuroscience: A Handbook of the Social and Cultural Contexts of Neuroscience brings together multi-disciplinary scholars from around the world to explore key social, historical and philosophical studies of neuroscience, and to analyze the socio-cultural implications of recent advances in the field. This text’s original, interdisciplinary approach explores the creative potential for engaging experimental neuroscience with social studies of neuroscience while furthering the dialogue between neuroscience and the disciplines of the social sciences and humanities. Critical Neuroscience transcends traditional skepticism, introducing novel ideas about ‘how to be critical’ in and about science.
Annual Report
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