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Biomolecular Simulations
Over the past 40 years the field of molecular simulations has evolved from picosecond studies of isolated macromolecules in vacuum to studies of complex, chemically heterogeneous biological systems consisting of millions of atoms, with the simulation time scales spanning up to milliseconds. In Biomolecular Simulations: Methods and Protocols, expert researchers illustrate many of the methods commonly used in molecular modelling of biological systems, including methods for electronic structure calculations, classical molecular dynamics simulations and coarse-grained techniques. A selection of advanced techniques and recent methodological developments, which rarely find coverage in traditional ...
New Advances on Zika Virus Research
Zika virus (ZIKV) is a mosquito-borne member of the Flaviviridae family that historically has been associated with mild febrile illness. However, the recent outbreaks in Brazil in 2015 and its rapid spread throughout South and Central America and the Caribbean, together with its association with severe neurological disorders—including fetal microcephaly and Guillain-Barré syndrome in adults—have changed the historic perspective of ZIKV. Currently, ZIKV is considered an important public health concern that has the potential to affect millions of people worldwide. The significance of ZIKV in human health and the lack of approved vaccines and/or antiviral drugs to combat ZIKV infection have triggered a global effort to develop effective countermeasures to prevent and/or treat ZIKV infection. In this Special Issue of Viruses, we have assembled a collection of 32 research and review articles that cover the more recent advances on ZIKV molecular biology, replication and transmission, virus–host interactions, pathogenesis, epidemiology, vaccine development, antivirals, and viral diagnosis.
German Baking
Made in Germany ist auf der ganzen Welt ein Qualitätsmerkmal – auch bei Gebäck. Kein Wunder, dass Roggenbrot, Schwarzwälder Kirsch, Brezeln und Co. so beliebt sind. Dr. Oetker präsentiert nun mehr als 200 der beliebtesten deutschen Backrezepte aus dem Erfolgsbuch "Backen macht Freude" in englischer Sprache. Neben Klassikern wie Marble Cake, Nut twists, Kugelhopf Cake, Apple strudel, Onion slices und Rye bread finden sich in dem Buch moderne Leckerbissen wie Amerikaner cookies, Chocolate slices, Bacon waffles, Red currant meringue cake, Almond cookie flan und Sweet poppy croissants. Für jeden Anlass das perfekte Gebäck. Dank der Schritt-für-Schritt-Anleitungen und Bilder gelingen diese Rezepte im Handumdrehen. "German Baking" ist ein ideales Souvenir für Touristen, ein praktisches Gastgeschenk für Austauschschüler und Erasmusstudenten – einfach ein Must-have für alle Fans der deutschen Küche.
Medicinal Chemistry
This is an valuable introduction to medicinal chemistry for new graduates and PhDs. It will also serve to update more experienced scientists on the newer technologies in the field.
Children's Human Rights
Childrens human rights are regularly violated around the world. Child soldiers, child slavery, and child prostitution are some of the more graphic examples this books deals with, but hungry, sick, and orphaned children are equally at risk and more prevalent. In the United States, children suffer similar abuses, but some are unique to the United States justice system. Unlike most of the rest of the world, the U.S. is a well-developed western nation in which juvenile offenders can be tried as adults and subjected to capital punishment. This book brings together a wide array of original essays from a variety of academic and practitioner perspectives on human rights and the status of children. The details are disturbing the message, powerful We must vigorously extend the universal declaration of human rights to the most vulnerable humans of all--the children of the world, starting at home in the United States.
N-Heterocyclic Carbenes in Organocatalysis
Summarizing the emerging field of N-heterocyclic carbenes used in organocatalysis, this is an excellent overview of the synthesis and applications of NHCs focusing on carbon-carbon and carbon-heteroatom bond formation. Alongside comprehensive coverage of the synthesis, characteristics and applications, this handbook and ready reference also includes chapters on NHCs for polymerization reactions and natural product synthesis.
