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How Tobacco Smoke Causes Disease
This report considers the biological and behavioral mechanisms that may underlie the pathogenicity of tobacco smoke. Many Surgeon General's reports have considered research findings on mechanisms in assessing the biological plausibility of associations observed in epidemiologic studies. Mechanisms of disease are important because they may provide plausibility, which is one of the guideline criteria for assessing evidence on causation. This report specifically reviews the evidence on the potential mechanisms by which smoking causes diseases and considers whether a mechanism is likely to be operative in the production of human disease by tobacco smoke. This evidence is relevant to understanding how smoking causes disease, to identifying those who may be particularly susceptible, and to assessing the potential risks of tobacco products.
Food in Early Modern Europe
This unique book examines food's importance during the massive evolution of Europe following the Middle Ages.
Endobronchial Ultrasonography
Endobronchial ultrasonography (EBUS) is an exciting and still developing diagnostic tool that has added significantly to the diagnosis and staging of lung cancer and other thoracic diseases. Co-authored by one of the technology's pioneers, this book helps the reader to use EBUS to diagnose and stage lung cancer and a variety of different tumours of the chest region. The second edition of Endobronchial Ultrasonography covers all of the standard techniques and the very latest developments and guidelines involved in EBUS, combining two common procedures, bronchoscopy and real-time ultrasonography, allowing physicians to obtain precise biopsies of lymph nodes and masses within the chest cavity.
Intensity-Modulated Radiation Therapy
Clinical conformal radiotherapy is the holy grail of radiation treatment and is now becoming a reality through the combined efforts of physical scientists and engineers, who have improved the physical basis of radiotherapy, and the interest and concern of imaginative radiotherapists and radiographers. Intensity-Modulated Radiation Therapy de
Practical Cardiac Electrophysiology
Electrophysiology studies test the electrical activity of the heart to determine the source of an arrhythmia. This book is a comprehensive guide to cardiac electrophysiology providing a thorough understanding of the mechanisms of arrhythmias and therapeutic interventions used in their treatment. Beginning with an introduction to cardiac electrophysiology and the fundamentals of cardiac anatomy, imaging, mapping and ablation, the following sections cover the diagnosis and management of different types of arrhythmia. The final section discusses miscellaneous topics including entrainment, provocative drug testing in the electrophysiology lab, and catheter ablation in children. The book is highly illustrated with nearly 300 images and tables and each chapter concludes with a summary highlighting the main points of the topic and offers suggestions for further reading. Key points Comprehensive guide to diagnosis and treatment of cardiac arrhythmias Provides thorough overview of cardiac anatomy, imaging, mapping and ablation Includes other topics such as provocative drug testing and catheter ablation in children Highly illustrated with nearly 300 images and tables
The Cambridge Handbook of Instructional Feedback
This book brings together leading scholars from around the world to provide their most influential thinking on instructional feedback. The chapters range from academic, in-depth reviews of the research on instructional feedback to a case study on how feedback altered the life-course of one author. Furthermore, it features critical subject areas - including mathematics, science, music, and even animal training - and focuses on working at various developmental levels of learners. The affective, non-cognitive aspects of feedback are also targeted; such as how learners react emotionally to receiving feedback. The exploration of the theoretical underpinnings of how feedback changes the course of instruction leads to practical advice on how to give such feedback effectively in a variety of diverse contexts. Anyone interested in researching instructional feedback, or providing it in their class or course, will discover why, when, and where instructional feedback is effective and how best to provide it.
Mosaicism in Human Skin
This second edition offers a fully revised and updated work on a rapidly growing field of knowledge, and was prepared by two experts whose goal was to explain the molecular basis of mosaic skin disorders in a language that is accessible for practicing physicians and medical students alike. It presents a timely and comprehensive overview of the strikingly manifold patterns and peculiarities of mosaic skin disorders in a straightforward, reader-friendly way that will help physicians to further improve genetic counseling and treatment outcomes. The first two parts of the book are devoted to the mechanisms and patterns of cutaneous mosaicism, and include an explanation of genomic and epigenetic ...
Index Medicus
Vols. for 1963- include as pt. 2 of the Jan. issue: Medical subject headings.
Boronic Acids
For the first time, the whole field of organoboronic acids is presented in one comprehensive handbook. Professor Dennis Hall, a rising star within the community, covers all aspects of this important substance class, including applications in chemistry, biology and medicine. Starting with an introduction to the structure, properties, and preparation of boronic acid derivatives, together with an overview of their reactions and applications, the book goes on to look at metal-catalyzed borylation of alkanes and arenas, coupling reactions and rhodium-catalyzed additions of boronic acids to alkenes and carbonyl compounds. There follows chapters on copper-promoted C-O and C-N cross-coupling of boronic acids, recent applications in organic synthesis, as well as alpha-haloalkylboronic esters in asymmetric synthesis. Later sections deal with cycloadditions, organoboronic acids, oxazaborolidines as asymmetric inducers, and boronic acid based receptors and sensors. The whole is rounded off with experimental procedures, making this invaluable reading for organic, catalytic and medicinal chemists, as well as those working in organometallics.
